RAB0078
Human MCP-3 / CCL7 ELISA Kit
for serum, plasma, cell culture supernatant and urine
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About This Item
UNSPSC Code:
41116158
NACRES:
NA.32
Recommended Products
species reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
capture ELISA: suitable
input
sample type serum
sample type cell culture supernatant(s)
sample type urine
sample type plasma
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 20 pg/mL
standard curve range: 24.58-6000 pg/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... CCL7(6354)
General description
The Human MCP-3 (Monocyte Chemoattractant Protein-3) ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme- linked immunosorbent assay for the quantitative measurement of human MCP-3 in serum, plasma, cell culture supernatants and urine.
Immunogen
Recombinant Human MCP3
Application
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Biochem/physiol Actions
Monocyte-chemotactic protein 3 (MCP3), also known as chemokine (C-C motif) ligand 7 (CCL7), has an ability to attract and activate a large panel of leukocytes including monocytes, eosinophils, basophils, dendritic cells, natural killer cells and activated T lymphocytes. This property of the protein makes it favorable for antitumor therapy. Mutation in the gene is associated with the development of Crohn′s Disease (CD). Elevated expression of the gene contributes to the development of gastric cancer (GC). Thus, it acts as a potent diagnostic marker for GC.
Other Notes
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
Kit Components Also Available Separately
Product No.
Description
SDS
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Met. Corr. 1
Storage Class Code
8A - Combustible corrosive hazardous materials
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The Genomics of Autoimmune Disease in the Era of Genome-Wide Association Studies and Beyond
Lessard CJ, et al.
Autoimmunity Reviews, 11(4), 267-275 (2012)
MCP?3 (CCL7) delivered by parvovirus MVMp reduces tumorigenicity of mouse melanoma cells through activation of T lymphocytes and NK cells
Wetzel K, et al.
International Journal of Cancer. Journal International Du Cancer, 120(6), 1364-1371 (2007)
CCL7 and CCL21 overexpression in gastric cancer is associated with lymph node metastasis and poor prognosis
Hwang TL, et al.
World Journal of Gastroenterology, 18(11), 1249-1249 (2012)
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