GST fusion protein corresponding to amino acids 180-610 of rat p190 RhoGAP.
Other Notes
RhoGAP appears to couple signal transduction via Ras and Rho through its association with RasGAP.
Physical form
Solution in 0.1 M Tris-glycine, pH 7.4, containing 0.15 sodium chloride and 0.05% sodium azide.
Preparation Note
Purified using protein G.
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The Journal of cell biology, 218(9), 3060-3076 (2019-07-17)
SRC and ERK kinases control many cell biological processes that promote tumorigenesis by altering the activity of oncogenic and tumor suppressor proteins. We identify here a physiological interaction between DLC1, a focal adhesion protein and tumor suppressor, with SRC and
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