M4154
β-N-Methylamino-L-alanine hydrochloride
Synonym(s):
L-BMAA
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About This Item
Empirical Formula (Hill Notation):
C4H10N2O2 · HCl
CAS Number:
Molecular Weight:
154.60
MDL number:
UNSPSC Code:
12352200
Recommended Products
storage temp.
2-8°C
SMILES string
CNCC(N)C(O)=O
Biochem/physiol Actions
Neuroexcitotoxic amino acid; may be involved in Guam amyotrophic lateral sclerosis
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Estefanía de Munck et al.
Environmental toxicology and pharmacology, 35(2), 193-199 (2013-01-19)
β-N-methylamino-(L)-alanine (L)-BMAA) is a neurotoxic amino acid, found in the majority of cyanbacterial genera tested. Evidence for implication of (L)-BMAA in neurodegenerative disorders, like amyotrophic lateral sclerosis (ALS), relies on bioaccumulation and biomagnification from symbiotic cyanobacteria. The involvement of (L)-BMAA
Valeska Contardo-Jara et al.
Ecotoxicology and environmental safety, 88, 72-78 (2012-11-28)
Four different aquatic plants, the Pteridophyte Lomariopsis lineata and the Bryophytes Fontinalis antipyretica, Riccia fluitans and Taxiphyllum barbieri, were tested for their capacity to absorb the neurotoxin β-N-Methylamino-L-alanine (BMAA) from water and thus their possible applicability in a "Green Liver
Oskar Karlsson et al.
Toxicological sciences : an official journal of the Society of Toxicology, 130(2), 391-404 (2012-08-09)
The cyanobacterial toxin β-N-methylamino-L-alanine (BMAA) has been proposed to contribute to neurodegenerative disease. We have previously reported a selective uptake of BMAA in the mouse neonatal hippocampus and that exposure during the neonatal period causes learning and memory impairments in
Steven A Cohen
The Analyst, 137(9), 1991-2005 (2012-03-17)
The non-protein amino acid L-α-amino-β-methylaminopropionic acid (BMAA) has been linked to several neurodegenerative diseases. Its presence in trace amounts in complex sample such as bacterial, plant and mammalian tissue extracts and hydrolyzates makes analysis a complicated process requiring good analytical
The emerging science of BMAA: do cyanobacteria contribute to neurodegenerative disease?
Wendee Holtcamp
Environmental health perspectives, 120(3), A110-A116 (2012-03-03)
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