L6895
Lipid A, monophosphoryl from Salmonella enterica serotype minnesota Re 595 (Re mutant)
lyophilized powder, TLR ligand tested
Synonym(s):
Monophosphoryl Lipid A from Salmonella
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| Size/SKU | Availability | Price |
|---|---|---|
1 mg | Check Cart for Availability | €257.00 |
5 mg | Check Cart for Availability | €1,100.00 |
About This Item
biological source
Salmonella enterica (serotype minnesota Re 595 Re mutant)
Quality Segment
form
lyophilized powder
impurities
<0.2% Ketodeoxyoctonate (KDO)
shipped in
ambient
storage temp.
2-8°C
Application
Lipid A molecules compose the lipid membrane anchoring core components of endotoxins produced by Gram-negative bacteria. Lipid A molecules induce immune responses. Structually, lipid A molecules are composed of two glucosamine units with varied, species dependent, fatty acyl chain numbers and identity and degree of phosphorylation.
Lipid A, monophosphoryl from Salmonella enterica serotype minnesota Re 595 may be used in comparative assessment of the antigenicity of specific structures within different LPA molecules and analogues.
Lipid A, monophosphoryl from Salmonella enterica serotype minnesota Re 595 may be used in comparative assessment of the antigenicity of specific structures within different LPA molecules and analogues.
Biochem/physiol Actions
Lipid A has immunostimulatory adjuvant activity including macrophage, T-cell, and B-cell activation. Research has shown Lipid A has greater Th1 than Th2 stimulation.
Lipopolysaccharides (LPSs) are characteristic components of the cell wall of Gram-negative bacteria. LPS and its lipid A moiety stimulate cells of the innate immune system by the Toll-like receptor 4 (TLR4), a member of the Toll-like receptor protein family, which recognizes common pathogen-associated molecular-patterns (PAMPs).
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This Item | |||
|---|---|---|---|
| biological source Salmonella enterica (serotype minnesota Re 595 Re mutant) | biological source Escherichia coli (F583 Rd mutant) | biological source Escherichia coli (F583 Rd mutant) | biological source - |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| form lyophilized powder | form lyophilized powder | form lyophilized powder | form liquid |
| shipped in ambient | shipped in ambient | shipped in ambient | shipped in ambient |
| Quality Level 300 | Quality Level 200 | Quality Level 200 | Quality Level 200 |
| impurities <0.2% Ketodeoxyoctonate (KDO) | impurities <0.2% Ketodeoxyoctonate (KDO) | impurities - | impurities - |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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