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K4138

Sigma-Aldrich

Ketamine hydrochloride/xylazine hydrochloride solution

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
12352116
PubChem Substance ID:
NACRES:
NA.77

form

aqueous solution

Quality Level

drug control

USDEA Schedule III; stupéfiant (France); regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain)

storage temp.

2-8°C

SMILES string

Cl.Cl.Cc1cccc(C)c1NC2=NCCCS2.CNC3(CCCCC3=O)c4ccccc4Cl

InChI

1S/C13H16ClNO.C12H16N2S.2ClH/c1-15-13(9-5-4-8-12(13)16)10-6-2-3-7-11(10)14;1-9-5-3-6-10(2)11(9)14-12-13-7-4-8-15-12;;/h2-3,6-7,15H,4-5,8-9H2,1H3;3,5-6H,4,7-8H2,1-2H3,(H,13,14);2*1H

InChI key

IYJHJWJNWIPQFJ-UHFFFAOYSA-N

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Biochem/physiol Actions

This is a solution of ketamine hydrochloride, an NMDA receptor antagonist, and xylazine hydrochloride, an α2- adrenergic receptor agonist.

Other Notes

Telephone orders are not accepted for this product..

Kit Components Only

Product No.
Description

  • Ketamine hydrochloride 80 mg/mL

  • Xylazine hydrochloride 6 mg/mL

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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To evaluate the efficacy of prostaglandin antagonists on blood-retinal barrier breakdown induced by anterior segment intraocular simulated surgery. Rats were randomly assigned to a negative control group, model group, nonsteroidal anti-inflammatory drugs prophylactic treatment group, nonsteroidal anti-inflammatory drugs treatment group
Yibin Kang
Methods in molecular biology (Clifton, N.J.), 568, 7-19 (2009-07-08)
Metastatic spread of cancer cells from the primary tumors to distant vital organs, such as lung, liver, brain, and bone, is responsible for the majority of cancer-related deaths. Cancer stem cells are likely to play essential roles in the metastatic
Mao-Song Xie et al.
Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 222(1), 42-47 (2007-12-22)
To develop a practical rat model of blood-retinal barrier (BRB) breakdown induced by anterior segment intraocular surgery. A 27-gauge needle attached to infusion tubing running to a bottle of balanced salt solution was inserted through the limbus into the rat
Doyun Lee et al.
Nature protocols, 9(12), 2784-2795 (2014-11-07)
Intracellular recording allows precise measurement and manipulation of individual neurons, but it requires stable mechanical contact between the electrode and the cell membrane, and thus it has remained challenging to perform in behaving animals. Whole-cell recordings in freely moving animals
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International journal of ophthalmology, 10(12), 1824-1829 (2017-12-21)
To clarify the mechanism of infliximab treatment in diabetic macular edema (DME) and to provide a new alternative therapy for DME. Rats were randomly divided into the control group, the model group and the infliximab treatment group. A diabetic rat

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