Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

I2279

Sigma-Aldrich

IMID-4F hydrochloride

solid, solubility: >9 mg/mL in H2O, soluble

Synonym(s):

2-[N-(2,6-dichlorophenyl)-N-(4-fluorobenzyl)amino]-2-imidazoline hydrochloride

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C16H14Cl2FN3 ·HCl
CAS Number:
1049740-09-1
Molecular Weight:
374.67
MDL number:
MFCD03452939
UNSPSC Code:
12352202
PubChem Substance ID:
24278489
NACRES:
NA.77

Assay

≥98%

form

solid

color

white

solubility

H2O: soluble >9 mg/mL

SMILES string

Cl[H].Fc1cccc(CN(C2=NCCN2)c3c(Cl)cccc3Cl)c1

InChI

1S/C16H14Cl2FN3.ClH/c17-13-5-2-6-14(18)15(13)22(16-20-7-8-21-16)10-11-3-1-4-12(19)9-11;/h1-6,9H,7-8,10H2,(H,20,21);1H

InChI key

TWVCONNNZSKLLX-UHFFFAOYSA-N

Biochem/physiol Actions

Novel imidazoline-based K(ATP) channel blocker.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
100K4719

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

G A McPherson et al.
British journal of pharmacology, 128(8), 1636-1642 (1999-12-10)
1. The functional and electrophysiological effects of IMID-4F (2-[N-(2, 6-dichlorophenyl)-N-(4-flurorobenzyl)amino]imidazoline), a fluoro-benzyl derivative of clonidine, on vascular K(ATP) channels were investigated. In pig coronary artery, IMID-4F inhibited the vasorelaxation response to the K(ATP) channel opener levcromakalim with a pK(B) value
K Bell et al.
Naunyn-Schmiedeberg's archives of pharmacology, 362(2), 145-151 (2000-08-29)
In this study the activity of a number of novel imidazoline-based compounds (IMID series) was assessed by functional and binding studies to determine their actions at K(ATP) channels. The novel compounds, which we synthesised, were methoxy-, methyl-, butyl- and fluorophenyl

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service