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D9772

Sigma-Aldrich

1,2-Dipiperidinoethane

Synonym(s):

1,1′-(1,2-Ethanediyl)bispiperidine

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About This Item

Empirical Formula (Hill Notation):
C12H24N2
CAS Number:
1932-04-3
Molecular Weight:
196.33
EC Number:
217-692-7
UNSPSC Code:
12352103

density

0.92 g/mL at 25 °C (lit.)

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Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

113 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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B M Baron et al.
Brain research, 331(1), 164-167 (1985-04-01)
Dipiperidinoethane (DPE) administration produces seizures and CNS lesions. Here we elucidate the cholinergic origin of DPE toxicity. DPE is both an acetylcholinesterase (AChE) inhibitor and a muscarinic antagonist. This dual action negates most of the toxic effects of the compound
Excitatory transmitters and epilepsy-related brain damage.
J W Olney
International review of neurobiology, 27, 337-362 (1985-01-01)
Status epilepticus in the limbic system: biochemical and pathological changes.
R C Collins et al.
Advances in neurology, 34, 277-288 (1983-01-01)
J W Olney
Advances in experimental medicine and biology, 203, 631-645 (1986-01-01)
Here I have reviewed evidence from electron microscopic studies showing that each of several sustained limbic seizure syndromes is associated with a type of acute brain damage which is ultrastructurally indistinguishable from the brain damage induced by Glu and other
J W Olney et al.
Advances in neurology, 44, 857-877 (1986-01-01)
It is well established that the putative excitatory neurotransmitters, glutamate (Glu) and aspartate (Asp), are neurotoxins that have the potential of destroying central neurons by an excitatory mechanism. Kainic acid (KA), a rigid structural analog of Glu, powerfully reproduces the
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