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A9074

Sigma-Aldrich

2-Amino-2-methyl-1,3-propanediol

BioXtra, pH 10.0-12.0 (20 °C, 0.5 M in H2O), ≥99%

Synonym(s):

AMPD, Ammediol

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About This Item

Linear Formula:
(HOCH2)2C(NH2)CH3
CAS Number:
115-69-5
Molecular Weight:
105.14
Beilstein:
635708
EC Number:
204-100-7
MDL number:
MFCD00004678
UNSPSC Code:
12161700
PubChem Substance ID:
24891223

vapor density

3.63 (vs air)

vapor pressure

~10 mmHg ( 152 °C)

product line

BioXtra

Assay

≥99%

impurities

<0.005% Phosphorus (P)
<0.1% Insoluble matter

ign. residue

<0.1%

pH

10.0-12.0 (20 °C, 0.5 M in H2O)

useful pH range

7.8-9.7

pKa (25 °C)

8.8

bp

151 °C/10 mmHg (lit.)

mp

100-110 °C (lit.)

solubility

H2O: 0.5 M at 20 °C, clear, colorless

anion traces

chloride (Cl-): <0.05%
sulfate (SO42-): <0.05%

cation traces

Al: <0.001%
Ca: <0.0005%
Cu: <0.0005%
Fe: <0.0005%
K: <0.005%
Mg: <0.0005%
NH4+: <0.05%
Na: <0.005%
Pb: <0.001%
Zn: <0.0005%

SMILES string

CC(N)(CO)CO

InChI

1S/C4H11NO2/c1-4(5,2-6)3-7/h6-7H,2-3,5H2,1H3

InChI key

UXFQFBNBSPQBJW-UHFFFAOYSA-N

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Application

Buffer component in a SDS-gradient gel electrophoresis system that separates polypeptides in the molecular weight range of 1500 to 100,000. Used as a spacer in isotachophoresis of proteins. Also used as a buffer for the determination of alkaline phosphatase activity.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

>212.0 °F

Flash Point(C)

> 100 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
048K00821
107K01513
107K01512
107K01511
047K01611

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Takayuki Yakura et al.
Chemical & pharmaceutical bulletin, 55(9), 1385-1389 (2007-09-11)
Dirhodium(II)-catalyzed C-H amination reaction of (S)-3-(tert-butyldimethylsilyloxy)-2-methylpropyl carbamate, which was easily prepared from methyl (S)-2-methyl-3-hydroxypropanoate, proceeded more smoothly than those of their 2-(methoxycarbonyl)propyl derivative to give the corresponding oxazolidinone in excellent yield. The resulting oxazolidinone was converted efficiently into both (R)-monoprotected
M Sigrist et al.
Biochimica et biophysica acta, 1098(2), 191-200 (1992-01-16)
The amino acid sequences of more than 40 apoproteins of the light-harvesting complex associated with Photosystem II (LHC II) of various plants have been deduced by sequencing their corresponding genes. These highly conserved sequences fall into two major categories, type
W Thormann et al.
Electrophoresis, 11(4), 298-304 (1990-04-01)
The isotachophoretic behavior of a model protein, serum albumin, was examined (i) by computer simulation, (ii) by capillary isotachophoresis in HPE 100 and Tachophor 2127, (iii) by continuous flow isotachophoresis in Elphor VaP 22 and the BIO-STREAM Separator and (iv)
A A Lemmens et al.
Journal of chromatography, 320(1), 193-197 (1985-02-22)
Isotachophoresis seems a likely candidate for a reference method, as it is more accurate and precise than common routine methods. The response is highly linear and depends on a well defined transport number of the leading ion, stability of the
H Kikuchi et al.
The Tohoku journal of experimental medicine, 173(4), 391-397 (1994-08-01)
The method by MacQueen and Plaut was modified to devise simple microdetermination method of l-lactate which is applicable to deproteinized blood sample. Blood was deproteinized with addition of 25% (w/w) trichloroacetic acid (TCA), and 0.075 M 2-amino-2-methyl-1, 3-propanediole (AMPD) was
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