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39488

Pyrimidine nucleoside phosphorylase

recombinant, expressed in E. coli, ≥1300 U/mL

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Size/SKUAvailabilityPrice
1 mL
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€190.00
5 mL
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€742.00

About This Item

CAS Number:
MDL number:
UNSPSC Code:
12352204
NACRES:
NA.54
EC Number:
Specific activity:
≥1300 U/mL
Recombinant:
expressed in E. coli

€190.00


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recombinant

expressed in E. coli

Quality Segment

form

liquid

specific activity

≥1300 U/mL

relevant disease(s)

cancer

storage temp.

−20°C

Application

Pyrimidine nucleoside phosphorylase (PyNPase) may be used as a marker to predict the malignant potential of breast cancer, especially lymph node metastasis[1]. PyNPase is used to study breast cancer, specifically its role in angiogenesis[1].

Biochem/physiol Actions

Pyrimidine nucleoside phosphorylase (PyNPase) is a glycosyltransferase that catalyzes the conversion of pyrimidine nucleoside and phosphate to a pyrimidine base and α-D-ribose 1-phosphate[2]. PyNPase plays a significant role in breast cancer angiogenesis[1].

Other Notes

One unit will convert 1 μmole each of thymidine and phosphate to thymine and 2-deoxyribose 1-phosphate per minute at pH 7.4 and 25°C

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This Item
N2415540221N3665
specific activity

≥1300 U/mL

specific activity

≥10 units/mg protein

specific activity

≥25 units/mg protein

specific activity

≥70 units/mg protein

recombinant

expressed in E. coli

recombinant

expressed in E. coli

recombinant

expressed in E. coli

recombinant

expressed in E. coli

form

liquid

form

lyophilized powder

form

liquid

form

lyophilized powder

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

Quality Level

100

Quality Level

200

Quality Level

100

Quality Level

200

relevant disease(s)

cancer

relevant disease(s)

-

relevant disease(s)

-

relevant disease(s)

-


pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Resp. Sens. 1

Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



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