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Y0000391

Betahistine dihydrochloride

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Methyl[2-(2-pyridyl)ethyl]amine dihydrochloride

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About This Item

Empirical Formula (Hill Notation):
C8H12N2 · 2HCl
CAS Number:
5579-84-0
Molecular Weight:
209.12
MDL number:
MFCD00012813
UNSPSC Code:
41116107
PubChem Substance ID:
329830930
NACRES:
NA.24
Pricing and availability is not currently available.

grade

pharmaceutical primary standard

API family

betahistine

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

Cl.CNCCc1ccccn1

InChI

1S/C8H12N2.2ClH/c1-9-7-5-8-4-2-3-6-10-8;;/h2-4,6,9H,5,7H2,1H3;2*1H

InChI key

XVDFMHARQUBJRE-UHFFFAOYSA-N

Gene Information

human ... HRH1(3269) , HRH3(11255)

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Betahistine dihydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Shigeru Hishinuma et al.
Biochemical pharmacology, 91(2), 231-241 (2014-07-30)
Differential binding sites for first- and second-generation antihistamines were indicated on the basis of the crystal structure of human histamine H1 receptors. In this study, we evaluated differences between the thermodynamic driving forces of first- and second-generation antihistamines for human

Questions

  1. What is the physical form of this product and its purity?

    1 answer

    1. This compound is in powder form. The product is supplied by the European Pharmacopoeia. Please see the links below to review the product information provided by the supplier:

      https://crs.edqm.eu/db/4DCGI/search?vSelectName=2&vContains=1&vtUserName=Y0000391&OK=Search&vTypeCRS=

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