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C2040

Supelco

Cloperastine hydrochloride

analytical standard

Synonym(s):

4-Chlorobenzhydryl 2-(1-piperidyl)ethyl ether

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About This Item

Empirical Formula (Hill Notation):
C20H24ClNO · HCl
CAS Number:
14984-68-0
Molecular Weight:
366.32
EC Number:
239-067-8
MDL number:
MFCD00079012
UNSPSC Code:
41116107
PubChem Substance ID:
329774924

grade

analytical standard

Quality Level

200

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

SMILES string

Cl.Clc1ccc(cc1)C(OCCN2CCCCC2)c3ccccc3

InChI

1S/C20H24ClNO.ClH/c21-19-11-9-18(10-12-19)20(17-7-3-1-4-8-17)23-16-15-22-13-5-2-6-14-22;/h1,3-4,7-12,20H,2,5-6,13-16H2;1H

InChI key

UNPLRYRWJLTVAE-UHFFFAOYSA-N

Application

Cloperastine hydrochloride may be used as an analytical standard for the quantification of cloperastine in biological samples using liquid chromatography coupled to tandem mass spectrometry.[1]
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

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[Effect of cloperastine on muco-ciliary clearance].
D Olivieri et al.
Archivio Monaldi per la tisiologia e le malattie dell'apparato respiratorio, 38(5-6), 219-223 (1983-09-01)
Yukoh Sakata et al.
International journal of pharmaceutics, 335(1-2), 12-19 (2006-11-23)
Tablets containing both paracetamol (PM) and cloperastine hydrochloride (CLH) in a combination formulation prepared by standard vertical granulation technology were found to have altered pharmaceutical properties. The hardness and disintegration time of tablets containing both PM and CLH gradually increased
Hao Li et al.
Journal of pharmaceutical and biomedical analysis, 51(3), 716-722 (2009-11-03)
A rapid and sensitive method based on liquid chromatography-tandem mass spectrometry (LC-MS/MS) for the simultaneous quantitation of paracetamol, caffeine, pseudoephedrine, chlorpheniramine and cloperastine in human plasma has been developed and validated. After sample preparation by liquid-liquid extraction, the analytes and
[The pharmacologic activity of 1(2-(p-chloro-alpha-phenylbenzyloxy)ethyl)piperidine (cloperastine)].
G Canti et al.
Bollettino chimico farmaceutico, 122(8), 384-392 (1983-08-01)
Nobuki Matsumoto et al.
Scientific reports, 11(1), 1492-1492 (2021-01-17)
Cancer therapy is often hampered by the disease's development of resistance to anticancer drugs. We previously showed that the autonomously upregulated product of fibroblast growth factor 13 gene (FGF13; also known as FGF homologous factor 2 (FHF2)) is responsible for
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