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861405

Sigma-Aldrich

Hoechst 33258

Synonym(s):

2′-(4-hydroxyphenyl)-5-(4-methyl-1-piperazinyl)-2,5′-bi-1H-benzimidazole trihydrochloride hydrate, bisBenzimide

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About This Item

Empirical Formula (Hill Notation):
C25H24N6O · 3HCl · xH2O
CAS Number:
Molecular Weight:
533.88 (anhydrous basis)
EC Number:
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:

Assay

≥98% (TLC)

form

powder

mp

>300 °C (lit.)

λmax

343 nm

SMILES string

Cl[H].Cl[H].Cl[H].[H]O[H].CN1CCN(CC1)c2ccc3[nH]c(nc3c2)-c4ccc5[nH]c(nc5c4)-c6ccc(O)cc6

Other Notes

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Shawn N Whitehead et al.
PloS one, 6(6), e20808-e20808 (2011-06-21)
Gangliosides, a member of the glycosphingolipid family, are heterogeneously expressed in biological membranes and are particularly enriched within the central nervous system. Gangliosides consist of mono- or poly-sialylated oligosaccharide chains of variable lengths attached to a ceramide unit and are
Yi Liu et al.
Stem cells (Dayton, Ohio), 26(4), 1065-1073 (2008-02-02)
Periodontitis is a periodontal tissue infectious disease and the most common cause for tooth loss in adults. It has been linked to many systemic disorders, such as coronary artery disease, stroke, and diabetes. At present, there is no ideal therapeutic
G A Daxhelet et al.
Analytical biochemistry, 179(2), 401-403 (1989-06-01)
The increase in fluorescence, upon interaction with several fluorescent dyes was found to depend on the base composition of DNA. 4',6-Diamidino-2-phenylindole-2 HCl and Hoechst 33258 which bind to AT base pairs show a logarithmic relation. This relation is linear when
Stud. Biophys., 125, 121-121 (1988)
Norman Zielke et al.
Genes & development, 22(12), 1690-1703 (2008-06-19)
Endoreplicating cells undergo multiple rounds of DNA replication leading to polyploidy or polyteny. Oscillation of Cyclin E (CycE)-dependent kinase activity is the main driving force in Drosophila endocycles. High levels of CycE-Cdk2 activity trigger S phase, while down-regulation of CycE-Cdk2

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