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71943

Sigma-Aldrich

Sodium salicylate

tested according to Ph. Eur.

Synonym(s):

Natrii salicylas, 2-Hydroxybenzoic acid sodium salt, Salicylic acid sodium salt, Sodium 2-hydroxybenzoate

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About This Item

Linear Formula:
HOC6H4COONa
CAS Number:
54-21-7
Molecular Weight:
160.10
Beilstein:
3732792
EC Number:
200-198-0
MDL number:
MFCD00002440
UNSPSC Code:
12352201
PubChem Substance ID:
329763648
NACRES:
NA.21

Agency

USP/NF
tested according to Ph. Eur.

Quality Level

100

form

crystals

color

white

useful pH range

6.85 (26.3 °C)

mp

>300 °C (lit.)

solubility

water: 575.7 g/L at 25 °C (77 °F)

application(s)

pharmaceutical (small molecule)

SMILES string

[Na+].Oc1ccccc1C([O-])=O

InChI

1S/C7H6O3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H,(H,9,10);/q;+1/p-1

InChI key

ABBQHOQBGMUPJH-UHFFFAOYSA-M

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Pictograms

Health hazardExclamation mark
GHS08,GHS07

Signal Word

Warning

Hazard Statements

H302,H319,H361d

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

208.9 °F - Pensky-Martens closed cup

Flash Point(C)

98.3 °C - Pensky-Martens closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCJ7211
BCCG9418
BCCG2202
BCCD4378
BCCD1203

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The Journal of pharmacology and experimental therapeutics, 339(3), 896-904 (2011-09-10)
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Rainer Amann et al.
European journal of pharmacology, 447(1), 1-9 (2002-07-11)
Aspirin (acetylsalicylic acid) is one of the most widely used drugs worldwide. It acetylates cyclooxygenases thereby irreversibly blocking the conversion of arachidonic acid to prostanoids. Biotransformation of aspirin yields salicylate, a compound that possesses similar anti-inflammatory potency as aspirin but
Itsuro Kazama et al.
Immunopharmacology and immunotoxicology, 34(5), 874-878 (2012-03-14)
Lymphocytes predominantly express delayed rectifier K(+)-channels (Kv1.3) in their plasma membranes, and the channels play crucial roles in the lymphocyte activation and proliferation. Since nonsteroidal anti-inflammatory drugs (NSAIDs), the most commonly used analgesic and antipyretic drugs, exert immunomodulatory effects, they
Yutaka Sumino et al.
Physical review. E, Statistical, nonlinear, and soft matter physics, 85(4 Pt 2), 046307-046307 (2012-06-12)
The dynamics of a viscoelastic Maxwell fluid is studied in a partially filled cylinder rotating around a horizontal axis. At low rotational velocity, the fluid behaves in the same manner as a viscous fluid. A thin fluid film is pulled
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