59964

Histamine

analytical standard

• Synonym(s): 2-(4-Imidazolyl)ethylamine
• Empirical Formula (Hill Notation): C₅H₉N₃
• CAS Number: 51-45-6
• Molecular Weight: 111.15
• Beilstein: 2012
• EC Number: 200-100-6
• MDL number: MFCD00005210
• UNSPSC Code: 85151701
• PubChem Substance ID: 329758639
• NACRES: NA.24

Properties

• grade: analytical standard
• Quality Level: 100
• Assay: ≥97.0% (TLC); ≥97.0% (anhydrous basis, NT)
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• impurities: ≤4.0% water
• color: white to light yellow
• bp: 167 °C/0.8 mmHg (lit.)
• mp: 83-84 °C (lit.)
• format: neat
• storage temp.: −20°C
• SMILES string: NCCc1c[nH]cn1
• InChI: 1S/C5H9N3/c6-2-1-5-3-7-4-8-5/h3-4H,1-2,6H2,(H,7,8)
• InChI key: NTYJJOPFIAHURM-UHFFFAOYSA-N
• Gene Information: human ... HRH1(3269)

Description

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Endogenous H₁ and H₂ histamine receptor agonist; H₁ activation mobilizes Ca²⁺; H₂ activation stimulates adenylate cyclase activity in neurons; activates nitric oxide synthetase; potent vasodilator.

Safety Information

• Pictograms: GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H301,H315,H317,H319,H334,H335
• Precautionary Statements: P280 - P301 + P310 + P330 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable