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Supelco

Bis(dimethylamino)dimethylsilane

for GC derivatization, LiChropur, ≥95.0% (GC)

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About This Item

Linear Formula:
[(CH3)2N]2Si(CH3)2
CAS Number:
Molecular Weight:
146.31
Beilstein:
1736095
EC Number:
MDL number:
UNSPSC Code:
41116105
PubChem Substance ID:
NACRES:
NA.22

grade

for GC derivatization

Quality Level

vapor density

>1 (vs air)

vapor pressure

1 mmHg ( 20 °C)

Assay

≥95.0% (GC)

form

liquid

quality

LiChropur

reaction suitability

reagent type: derivatization reagent
reaction type: Silylations

technique(s)

gas chromatography (GC): suitable

refractive index

n20/D 1.417 (lit.)
n20/D 1.418

bp

128-129 °C (lit.)

mp

−98 °C (lit.)

density

0.809 g/mL at 25 °C (lit.)

SMILES string

CN(C)[Si](C)(C)N(C)C

InChI

1S/C6H18N2Si/c1-7(2)9(5,6)8(3)4/h1-6H3

InChI key

QULMGWCCKILBTO-UHFFFAOYSA-N

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Application

Bis(dimethylamino)-dimethyl silane was used to silanize pH-sensitive microelectrodes, used to measure the membrane potential in oocytes, in an experimental procedure aimed towards cloning and characterising human electrogenic Na+-cotransporter isoform (hhNBC). It was also used for microelectrode measurements, in a study conducted to measure carbon dioxide transport through membranes.

Other Notes

Derivatization reagent for steroids: the (dimethylamino)dimethylsilyl derivatives can be analyzed by GC using a nitrogen-phosphorus detector; Protection of diols, diamines, etc.

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Pictograms

FlameCorrosion

Signal Word

Danger

Hazard Statements

Hazard Classifications

Flam. Liq. 2 - Skin Corr. 1B

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

19.4 °F - closed cup

Flash Point(C)

-7 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Cloning and characterization of a human electrogenic Na+-cotransporter isoform (hhNBC).
American Journal of Physiology. Cell Physiology, 276 (3), C576-C584 (1999)
Journal of Organometallic Chemistry, 294, 7-7 (1985)
Carbon dioxide transport through membranes.
Missner A
The Journal of Biological Chemistry, 283 (37), 25340-25347 (2008)
R.H. Cragg et al.
Journal of Organometallic Chemistry, 289, 23-23 (1985)
C.F. Poole et al.
Journal of Chromatographic Science, 17, 115-115 (1979)

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Results of a study involving the ability few Fluka silylating reagents to form GC-MS-compatible trimethylsilylmethyl derivatives of NSAIDs

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