MB1HC23CL3

Millistak+^® Depth Filter in μPOD format

B1HC, cellulose fiber, filtration area 0.0023 m², hydrophilic

• Synonym(s): Millistak+Depth Filter in Pod format, B1HC media series, 23 cm² surface area, Luer fitting connection
• UNSPSC Code: 23151806
• eCl@ss: 32031690
• NACRES: NB.24

Properties

• material: cellulose fiber ; filter aid (inorganic); glass fiber-reinforced polypropylene
• Quality Level: 400
• description: Post-centrifuge or settled permeate containing cellular particulate
• feature: hydrophilic
• manufacturer/tradename: Millistak+^®
• parameter: 1.0 bar max. differential pressure (15 psid) at 40 °C (Reverse); 2.1 bar max. differential pressure (30 psid) at 40 °C (Forward)
• H: 6.6 cm (2.6 in.)
• L: 8.9 cm (3.5 in.)
• filtration area: 0.0023 m²
• impurities: <0.25 EU/mL (LAL test, Aqueous extraction)
• gravimetric extractables: 420-750 mg/ft²
• input: sample type liquid
• conductivity: 3.64 – 10.5 μS/cm
• filter grade: B1HC
• shipped in: ambient

Description

General description

The Millistak+^® depth filter media is offered in a scalable, disposable format providing greater flexibility because of its unique modular design. The Millistak+^® MB1HC23CL3 comes in a μPOD format featuring a 6.6 cm (H) x 8.9 cm (L) and a filtration area of 0.0023 m².

This B1HC media series delivers optimal performance through a gradient density matri, ideal for secondary clarification post tangential flow filtration, or depth filtration or centrifugation applications. Millistak+^® Pod filters are available in three distinct series of media grades in order to meet your specific needs - DE, CE and HC.

The Millistak+^® Pod system is ideal for a wide variety of primary and secondary clarification applications, including cell cultures, yeast and E. coli lysates post centrifuge, E. coli refolds, media, vaccines, plasma proteins and sera.

Easy to Use

With the compact, modular design of our Millistak+^® new Pod system, you can increase productivity and shorten cycle times.

Installation and setup of the Pod system is simple and straightforward. The unique design of the disposable adapters and disposable manifolds makes it easy to connect the Pod filters to rest of the unit operations in the process. The self-contained and disposable nature of the system protects operators from exposure to biohazards and eliminates maintenance as well as cleaning validation requirements.

product water; post autoclave (1 cycle of 60 minutes at 123 °C) and pure water flush of 10 liter per ft²(100 L/m²) of media surface area

Application

Post-centrifuge or settled permeate containing cellular particulate

Features and Benefits

• Low hold-up volume for greater product yield
• Broad range of media types offered in single and multilayer products
• Millistak+^® HC dual-action media improves prefiltration and compresses clarification
• Flexible, modular format offers scalability from 5 to 12,000 liters or more
• Patented disposable design eliminates need for housing, CIP or cleaning validation
• Self-contained Pod filters protect operators from exposure to biohazards
• Robust construction is easy to use and set up
• Smaller footprint facilitates use in tight spaces

Specifications

Filter Grade: B1HC

Preparation Note

Sterilization Method
2 autoclave cycles of 60 minutes at 123 °C.

Analysis Note

Gravimetric Extractables: per 24-hour static soak in pure water; (type 1 DI water), post autoclave (1 cycle of 60 minutes at 123 °C) and pure water flush of 10 liters per ft² (100 L/m²) of media surface area

Legal Information

MILLISTAK+ is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 10-13 - German Storage Class 10 to 13
• WGK: nwg
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable