Recognizes the C-terminal region of all endothelins (amino acid residues 15-21) when used as a capture antibody in IRMA assays. The antibody does not cross-react with "big" endothelin.
Immunogen
Epitope: C-terminus
Application
Development of IRMA assays for ET-1 (CBL 85) and ET-3 (CBL 86)
Suitable for immunocytochemistry on frozen sections
Optimal working dilutions must be determined by the end user.
Research Category Neuroscience
Research Sub Category CNS Control of Metabolism
Hormones & Receptors
This Anti-Endothelin Antibody, C-terminus, clone 3G10 is validated for use in IC for the detection of Endothelin.
Physical form
Format: Purified
Protein A purified
The monoclonal is presented at in phosphate buffered saline containing 10mM sodium azide. We recommend that each laboratory determine an optimum working titre for use in its particular application.
Storage and Stability
For use within 1 month of purchase store at +4°C, for long term storage aliquot antibody into small volumes and store at -20°C.
Analysis Note
Control Expressed in lung, placental stem villi vessels and in cultured placental vascular smooth muscle cells
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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