There are two forms of Neuropilin: Neuropilin-1 and Neuropilin-2. These are non–tyrosine kinase receptors that bind to VEGF and semaphorins (SEMA3A, SEMA3B, and SEMA3F) and play an important role in the critical functioning of the nervous system. Neuropilin-2 is expressed in tumor cells, and mature and developing endothelial cells and vascular smooth muscle cells. This expression has been associated with tumor angiogenesis and progression.
Specificity
This antibody recognizes Neuropilin-2.
Immunogen
His-tagged partial recombinant rat Neuropilin-2 protein.
Application
Detect Neuropilin-2 using this Anti-Neuropilin-2 Antibody validated for use in WB, IH, IP & IF.
Quality
Evaluated by Western Blot in mouse P1 brain tissue lysate.
Western Blot Analysis: 1:1000 dilution of this antibody detected Neuropilin-2 on 10 µg of mouse P1 brain tissue lysate.
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