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biological source
goat
Quality Level
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
form
liquid
contains
≤0.1% sodium azide as preservative
species reactivity
human
manufacturer/tradename
Calbiochem®
availability
not available in Canada
storage condition
OK to freeze
avoid repeated freeze/thaw cycles
isotype
IgG
shipped in
ambient
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... CFH(3075)
General description
Anti-Factor H, goat polyclonal, recognizes Factor H in human. It is validated for Radial Immunodiffusion and Ouchterlony.
Goat polyclonal antibody supplied as undiluted serum. Recognizes Factor H.
Recognizes Factor H.
Immunogen
Human
purified, human factor H
Application
Radial Immunodiffusion (see comments)
Ouchterlony (≥ undiluted)
Ouchterlony (≥ undiluted)
Packaging
Please refer to vial label for lot-specific concentration.
Warning
Toxicity: Standard Handling (A)
Physical form
Undiluted serum.
Reconstitution
Following initial thaw, aliquot and freeze (-20°C).
Other Notes
This antibody has also been reported to work for radial immunodiffusion. Variables associated with assay conditions will dictate the proper working dilution.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Martin Ihnatko et al.
Frontiers in medicine, 8, 789972-789972 (2022-01-22)
COVID-19 vaccine-induced thrombotic thrombocytopenia (VITT) is a rare complication of adenoviral vector (ChAdOx1 nCoV-19) vaccine administration. It is presented as thrombocytopenia and thrombotic manifestations in various sites, especially in cerebral veins. Pulmonary emboli have been reported rarely. We present a
Diana Pauly et al.
Cell reports, 29(9), 2835-2848 (2019-11-28)
Complement dysregulation is a feature of many retinal diseases, yet mechanistic understanding at the cellular level is limited. Given this knowledge gap about which retinal cells express complement, we performed single-cell RNA sequencing on ∼92,000 mouse retinal cells and validated
Ashutosh Verma et al.
Infection and immunity, 78(5), 2053-2059 (2010-02-18)
The spirochete Leptospira interrogans is a highly invasive pathogen of worldwide public health importance. Studies from our laboratories and another have demonstrated that L. interrogans can acquire host plasminogen on its surface. Exogenous plasminogen activators can then convert bound plasminogen
David Ermert et al.
PLoS pathogens, 11(7), e1005043-e1005043 (2015-07-23)
Streptococcus pyogenes, also known as Group A Streptococcus (GAS), is an important human bacterial pathogen that can cause invasive infections. Once it colonizes its exclusively human host, GAS needs to surmount numerous innate immune defense mechanisms, including opsonization by complement
Anuj Pathak et al.
Nature communications, 9(1), 3398-3398 (2018-08-25)
Streptococcus pneumoniae evades C3-mediated opsonization and effector functions by expressing an immuno-protective polysaccharide capsule and Factor H (FH)-binding proteins. Here we use super-resolution microscopy, mutants and functional analysis to show how these two defense mechanisms are functionally and spatially coordinated
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