1.06431

tri-Sodium citrate 5,5-hydrate

EMPROVE^® ESSENTIAL, E 331

• Synonym(s): tri-Sodium citrate 5,5-hydrate
• Empirical Formula (Hill Notation): C₆H₅Na₃O₇ · 5.5H₂O
• CAS Number: 6858-44-2
• Molecular Weight: 357.15
• MDL number: MFCD00150032
• UNSPSC Code: 12352107
• E Number: E331
• EC Index Number: 200-675-3

Properties

• Quality Level: 500
• description: FU VIII grade
• product line: EMPROVE^® ESSENTIAL
• form: solid
• pH: 7.5-9.0 (20 °C, 50 g/L in H₂O)
• mp: >150 °C (anhydrous)
• solubility: 920 g/L
• application(s): liquid formulation; ophthalmics; pharmaceutical; semi-solid formulation; solid formulation
• storage temp.: 2-30°C
• InChI: 1S/11C6H8O7.11Na.2H2O/c11*7-3(8)1-6(13,5(11)12)2-4(9)10;;;;;;;;;;;;;/h11*13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;;;;;;;;;;2*1H2/q;;;;;;;;;;;11*+1;;/p-33
• InChI key: HEFYJRQSMQOKRW-UHFFFAOYSA-A

Description

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Tri-sodium citrate 5,5-hydrate is widely used in pharmaceutical formulations, typically as pH adjuster and buffer agent.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable