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biological source
rabbit
Quality Level
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
mouse, human
manufacturer/tradename
Upstate®
technique(s)
immunoprecipitation (IP): suitable
western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
dry ice
Gene Information
human ... TBX2(6909)
Specificity
TBX2
Immunogen
GST fusion protein corresponding to residues 554-702 of human TBX2
Application
Detect TBX2 also known as T-box 2 with Anti-TBX2 Antibody (Rabbit Polyclonal Antibody), that has been demonstrated to work in IP & WB.
Quality
routinely evaluated by immunoblot on RIPA lysates from MCF-7 human breast adenocarcinoma cells
Target description
74kDa
Physical form
antiserum with 0.05% sodium azide before the addition of glycerol to 30%
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Juan Aparicio-Blanco et al.
Drug delivery and translational research (2024-05-13)
Brain drug delivery is severely hindered by the presence of the blood-brain barrier (BBB). Its functionality relies on the interactions of the brain endothelial cells with additional cellular constituents, including pericytes, astrocytes, neurons, or microglia. To boost brain drug delivery
J J Jacobs et al.
Nature genetics, 26(3), 291-299 (2000-11-04)
To identify new immortalizing genes with potential roles in tumorigenesis, we performed a genetic screen aimed to bypass the rapid and tight senescence arrest of primary fibroblasts deficient for the oncogene Bmi1. We identified the T-box member TBX2 as a
Timo H Lüdtke et al.
Respiratory research, 22(1), 85-85 (2021-03-19)
Tbx2 encodes a transcriptional repressor implicated in the development of numerous organs in mouse. During lung development TBX2 maintains the proliferation of mesenchymal progenitors, and hence, epithelial proliferation and branching morphogenesis. The pro-proliferative function was traced to direct repression of
K L Redmond et al.
Oncogene, 29(22), 3252-3262 (2010-03-30)
T-box 2 (TBX2) is a transcription factor involved in mammary development and is known to be overexpressed in a subset of aggressive breast cancers. TBX2 has previously been shown to repress growth control genes such as p14(ARF) and p21(WAF1/cip1). In
Marina Kaiser et al.
Development (Cambridge, England), 148(8) (2021-04-03)
All epithelial components of the inner ear, including sensory hair cells and innervating afferent neurons, arise by patterning and differentiation of epithelial progenitors residing in a simple sphere, the otocyst. Here, we identify the transcriptional repressors TBX2 and TBX3 as
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