05-919
Anti-T-Cell Receptor Antibody, clone C305
culture supernatant, clone C305, Upstate®
Synonym(s):
T-Cell receptor antibody
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
biological source
mouse
Quality Level
antibody form
culture supernatant
antibody product type
primary antibodies
clone
C305, monoclonal
species reactivity
human
manufacturer/tradename
Upstate®
technique(s)
immunoprecipitation (IP): suitable
multiplexing: suitable
isotype
IgM
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... TRDD3(28523)
Specificity
Jurkat T-Cell Receptor
Immunogen
Jurkat T cells
Application
Anti-T-Cell Receptor Antibody, clone C305 detects level of T-Cell Receptor & has been published & validated for use in Mplex & IP.
Research Category
Inflammation & Immunology
Inflammation & Immunology
Research Sub Category
Immunoglobulins & Immunology
Immunoglobulins & Immunology
Quality
routinely used in bioassays to activate T cell receptor signaling cascades in Jurkat cells
Physical form
Concentrated culture supernatant
Storage and Stability
stable 2 years at -20°C from date of shipment
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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A Weiss et al.
The Journal of experimental medicine, 160(5), 1284-1299 (1984-11-01)
The association between T3 and the T cell antigen receptor was examined using the T3 bearing T cell leukemic line Jurkat. A monoclonal antibody, C305, was produced, which reacted with idiotypic-like determinants expressed on Jurkat. The molecule with which this
Joseph Lin et al.
The Journal of cell biology, 162(4), 673-682 (2003-08-13)
CD148 is a receptor-like protein tyrosine phosphatase up-regulated on T cells after T cell receptor (TCR) stimulation. To examine the physiologic role of CD148 in TCR signaling, we used an inducible CD148-expressing Jurkat T cell clone. Expression of CD148 inhibits
Pussadee Paensuwan et al.
Journal of immunology (Baltimore, Md. : 1950), 196(1), 448-458 (2015-11-22)
Ligand binding to the TCR causes a conformational change at the CD3 subunits to expose the CD3ε cytoplasmic proline-rich sequence (PRS). It was suggested that the PRS is important for TCR signaling and T cell activation. It has been shown
Nadia Martinez-Martin et al.
Nature communications, 7, 11473-11473 (2016-05-06)
Viruses encode secreted and cell-surface expressed proteins essential to modulate host immune defenses and establish productive infections. However, to date there has been no systematic study of the extracellular interactome of any human virus. Here we utilize the E3 proteins
Tim Kükenshöner et al.
Journal of molecular biology, 429(9), 1364-1380 (2017-03-30)
The binding of Src-homology 2 (SH2) domains to phosphotyrosine (pY) sites is critical for the autoinhibition and substrate recognition of the eight Src family kinases (SFKs). The high sequence conservation of the 120 human SH2 domains poses a significant challenge
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