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810282C

Avanti

TopFluor™ PE

Avanti Research™ - A Croda Brand 810282C

Synonym(s):

1-palmitoyl-2-(dipyrrometheneboron difluoride)undecanoyl-sn-glycero-3-phosphoethanolamine

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About This Item

Empirical Formula (Hill Notation):
C45H77BF2N3O8P
CAS Number:
1246355-64-5
Molecular Weight:
867.89
UNSPSC Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (810282C-1mg)
pkg of 5 × 1 mL (810282C-5mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 810282C

concentration

1 mg/mL (810282C-1mg)
1 mg/mL (810282C-5mg)

shipped in

dry ice

storage temp.

−20°C

General description

TopFluor has a moiety, called dipyrromethene boron difluoride. This fluorescent molecule is covalently attached to various lipid molecules. Phosphoethanolamine is a precursor to phosphatidylcholine and phosphatidylethanolamine.

Application

TopFluor® PE may be used as a fluorescently labeled lipid to replace the head labeled lipid (TFPE-head) to study the fusion efficiency of liposomes. It has also been used in the preparation of liposome.

Biochem/physiol Actions

Phosphoethanolamine participates in phospholipid metabolism. It has the ability to repress tumor growth both in vitro and in vivo.

Packaging

5 mL Amber Glass Screw Cap Vial (810282C-1mg)
5 mL Amber Glass Screw Cap Vial (810282C-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC
TopFluor is a trademark of Avanti Polar Lipids, LLC
Topamax is a registered trademark of Johnson & Johnson

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system, Liver,Kidney

WGK

WGK 3

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Single Particle Fluorescence Burst Analysis of Epsin Induced Membrane Fission
Brooks A, et al.
PLoS ONE, 10(3) (2015)
Influence of Environmental Conditions on the Fusion of Cationic Liposomes with Living Mammalian Cells
Kolasinac R, et al.
Nanomaterials, 9(7), 1025-1025 (2019)
Phosphoethanolamine and the danger of unproven drugs
Pondee N, et al.
Ecancermedicalscience (2016)
Fumonisin, Folate, and Neural Tube Defects
Comprehensive Toxicology, 12, 189-208 (2010)
Phosphoethanolamine and ethanolamine are decreased in Alzheimer's disease and Huntington's disease
Ellison David W, et al.
Brain Research, 417(2), 389-392 (1987)
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