Tyramine is extensively used in the preparation of a variety of hydrogels for biomedical applications.[1][2]
It is used as a key precursor in the total synthesis of (−)-mesembrine[3] and (−)-galanthamine.[4]
It can also be used in the preparation of tyramine-functionalized graphene quantum dots (GQDs) as fluorescence reporters for optical sensing of metabolites.[5]
Biochem/physiol Actions
Can enter catecholaminergic terminals and be released as a false transmitter.
European journal of medicinal chemistry, 48, 284-295 (2012-01-10)
Monoamine oxidase B (MAO-B) is a promising target for the treatment of neurodegenerative disorders. We report the synthesis and the biological evaluation of halogenated derivatives of 1-aryliden-2-(4-phenylthiazol-2-yl)hydrazines. The fluorinated series shows interesting activity and great selectivity toward the human recombinant
Enzyme-mediated fast in situ formation of hydrogels from dextran-tyramine conjugates.
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