Journal of the American Chemical Society, 126(14), 4534-4535 (2004-04-09)
Metabolic pathway engineering is a powerful tool to synthesize structurally diverse and complex chemicals via genetic manipulation of multistep catalytic systems involved in cell metabolism. Here, we report the rational design of a fatty acid biosynthetic pathway, Brevibacterium ammoniagenes fatty
Polyketide synthase-1 (PKS-1) is a novel type III polyketide synthase that catalyzes the biosynthesis of hexanoyl triacetic acid lactone in Cannabis sativa (Mexican strain). PKS-1 was overproduced in Escherichia coli, purified and finally crystallized in two different space groups. The
Irreversible inactivation of chicken liver fatty acid synthetase by its substrates acetyl and malonyl CoA. Effect of temperature and NADP n fatty acid and triacetic acid lactone synthesis.
K R Srinivasan et al.
Biochemical and biophysical research communications, 99(3), 920-927 (1981-04-15)
Biotechnology and bioengineering, 93(4), 727-736 (2005-10-26)
Native g2ps1-encoded 2-pyrone synthase (2-PS) from Gerbera hybrida, a mutant Brevibacterium ammoniagenes fatty acid synthase B (FAS-B) and two different mutants of Penicillium patulum 6-methylsalycilic acid synthase (6-MSAS) are examined to identify the best enzyme to recruit for the microbial
The Biochemical journal, 288 ( Pt 3), 839-846 (1992-12-15)
6-Methylsalicylic acid synthase has been isolated in homogeneous form from Penicillium patulum grown in liquid culture from a spore inoculum. The enzyme is highly susceptible to proteolytic degradation in vivo and in vitro, but may be stabilized during purification by
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.