F5312

Fmoc-(R)-propargyl-Ala-OH

• Synonym(s): (R)-N-Fmoc-α-propargyl-Ala-OH, (R)-N-Fmoc-α-propargylalanine
• Empirical Formula (Hill Notation): C₂₁H₁₉NO₄
• CAS Number: 1198791-65-9
• Molecular Weight: 349.38
• MDL number: MFCD12031694
• UNSPSC Code: 12352209
• PubChem Substance ID: 329799712
• NACRES: NA.22

Properties

• reaction suitability: reaction type: click chemistry
• application(s): peptide synthesis
• functional group: Fmoc
• shipped in: wet ice
• storage temp.: −20°C
• SMILES string: O=C(N[C@](C)(CC#C)C(O)=O)OCC1C2=CC=CC=C2C3=C1C=CC=C3
• InChI: 1S/C21H19NO4/c1-3-12-21(2,19(23)24)22-20(25)26-13-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h1,4-11,18H,12-13H2,2H3,(H,22,25)(H,23,24)/t21-/m1/s1
• InChI key: ZXOKSWZUJXKQCQ-OAQYLSRUSA-N

Description

Application

Alkyne amino acid, more stable for peptide stapling via click chemistry than propargylglycine.

Safety Information

• Pictograms: GHS09
• Signal Word: Warning
• Hazard Statements: H400
• Precautionary Statements: P273
• Hazard Classifications: Aquatic Acute 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable