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861804

Sigma-Aldrich

8-(Diethylamino)octyl-3,4,5-trimethoxybenzoate hydrochloride

97%

Synonym(s):

TMB 8 hydrochloride, TMB-8 · HCl

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About This Item

Linear Formula:
(CH3O)3C6H2CO2(CH2)8N(C2H5)2 · HCl
CAS Number:
Molecular Weight:
431.99
Beilstein:
5466611
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
Pricing and availability is not currently available.

Assay

97%

form

powder

mp

94-97 °C (lit.)

SMILES string

Cl[H].CCN(CC)CCCCCCCCOC(=O)c1cc(OC)c(OC)c(OC)c1

InChI

1S/C22H37NO5.ClH/c1-6-23(7-2)14-12-10-8-9-11-13-15-28-22(24)18-16-19(25-3)21(27-5)20(17-18)26-4;/h16-17H,6-15H2,1-5H3;1H

InChI key

KFJZVXKPPQIYCG-UHFFFAOYSA-N

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Application

  • Pharmacologically active inhibitor of hepatitis C virus life cycle

replaced by

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Patrycja Libako et al.
Magnesium research, 25(1), 12-20 (2012-03-30)
Divalent cations, especially calcium and magnesium, have been shown to play an important regulatory role in endothelial and immune cells. To learn more about the interaction of these two metals in the regulation of cell growth, we altered the calcium/magnesium
Hai-Long Wang et al.
The Chinese journal of physiology, 55(2), 101-107 (2012-05-09)
The purpose of this study was to determine the effects of an extract from Moringa oleifera (MO) on the development of monocrotaline (MCT)-induced pulmonary hypertension (PH) in Wistar rats. An ethanol extraction was performed on dried MO leaves, and HPLC
Daniel Floryk et al.
Cancer research, 65(24), 11588-11596 (2005-12-17)
Recently, we have reported that inosine 5'-monophosphate dehydrogenase inhibitors, such as mycophenolic acid (MPA), induce the differentiation of PC-3 cells, which are derived from a human androgen-independent prostate cancer, into cells with a phenotype resembling maturing prostate secretory cells. Here
Nicoletta Galeotti et al.
Neuropharmacology, 50(3), 309-316 (2005-10-27)
The role of intracellular calcium in the modulation of a depressant-like condition was investigated in the mouse forced swimming test. I.c.v. administration of TMB-8 (0.23-46.3 nmol per mouse), a blocker of Ca2+ release from intracellular stores, decreased the mouse immobility
Nancy S Krieger et al.
American journal of physiology. Renal physiology, 300(1), F91-F97 (2010-11-05)
In vivo chronic metabolic acidosis induces net Ca2+ efflux from bone, and incubation of neonatal mouse calvariae in medium simulating physiological metabolic acidosis induces bone resorption. It appears that activation of the proton (H+) receptor OGR1 in the osteoblast leads

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