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795674

Sigma-Aldrich

3-(Trimethylsilyl)pyridin-2-yl trifluoromethanesulfonate

95%

Synonym(s):

Garg 2,3-pyridyne precursor

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About This Item

Empirical Formula (Hill Notation):
C9H12F3NO3SSi
CAS Number:
Molecular Weight:
299.34
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

95%

form

liquid

refractive index

n/D 1.454

density

1.266 at 25 °C

storage temp.

2-8°C

InChI

1S/C9H12F3NO3SSi/c1-18(2,3)7-5-4-6-13-8(7)16-17(14,15)9(10,11)12/h4-6H,1-3H3

InChI key

SXIBFUWSBRRXRJ-UHFFFAOYSA-N

Application

Pyridyne precursor can be activated under mild fluoride conditions; which are highly reactive with dienes and other dipolariphiles (e.g. azides) to provide cycloaddition products containing an indole motif.

Pictograms

CorrosionExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Articles

New and efficient methods for the synthesis of functionalized heterocycles are highly sought after.

Related Content

The Garg group develops methods for the synthesis of natural products and pharmaceuticals. One key method pertains to heterocyclic arynes, such as indolynes and pyridynes, which are generated in situ from silyltriflate precursors under mild fluoride based reaction conditions.

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