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724475

Sigma-Aldrich

Poly(N-isopropylacrylamide-co-methacrylic acid-co-octadecyl acrylate)

5 mol % in methacrylic acid, 1 mol % in octadecyl acrylate, Mn 30,000-60,000

Synonym(s):

Poly(NIPAM-co-MAA-co-ODA), Polyacrylamide, functionalized polyNIPAM, functionalized polyacrylamide, polyNIPAM

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About This Item

Linear Formula:
(C6H11NO)m (C4H6O2)n (C21H40O2)p
UNSPSC Code:
12162002
NACRES:
NA.23

form

powder

mol wt

Mn 30,000-60,000

concentration

1 mol % in octadecyl acrylate
5 mol % in methacrylic acid

mp

>300 °C

General description

Intelligent Swelling/Collapsing copolymer that can be used as a temperature- and pH-sensitive material.[1][2]

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Quijada-Garrido; I.; Prior-Cabanillas; A.; Garrido; L.; Barrales-Rienda; J. M.
Macromolecules, 38, 7434-7434 (2005)
Salgado-Rodriguez; R.; Licea-Claverie; A.; Arndt; K. F.
Eur. Polymer J., 40, 1931-1931 (2004)

Articles

Poly(N-isopropylacrylamide), or PNIPAM, is a stimuli-responsive polymer that responds to changes in pH and temperature and has a LCST around 32 C.

Tissue engineering has become a key therapeutic tool in the treatment of damaged or diseased organs and tissues, such as blood vessels and urinary bladders.

By altering the physicochemical properties, smart or intelligent drug delivery systems can be designed to deliver therapeutic molecules on-demand. Learn more about the application of stimuli-responsive materials in drug delivery.

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