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70800

Sigma-Aldrich

5-Amino-1-naphthalenesulfonic acid

technical, ≥60.0% (T)

Synonym(s):

1-Naphthylamine-5-sulfonic acid, Laurent’s acid

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About This Item

Empirical Formula (Hill Notation):
C10H9NO3S
CAS Number:
Molecular Weight:
223.25
Beilstein:
2214149
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

grade

technical

form

powder

concentration

≥60.0% (T)

SMILES string

Nc1cccc2c(cccc12)S(O)(=O)=O

InChI

1S/C10H9NO3S/c11-9-5-1-4-8-7(9)3-2-6-10(8)15(12,13)14/h1-6H,11H2,(H,12,13,14)

InChI key

DQNAQOYOSRJXFZ-UHFFFAOYSA-N

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Pictograms

CorrosionExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 4 Dermal - Skin Corr. 1B

Storage Class Code

8B - Non-combustible corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Fluorescent nucleotide triphosphate substrates for snake venom phosphodiesterase.
S E Pollack et al.
Analytical biochemistry, 127(1), 81-88 (1982-11-15)
Brent A Mulder et al.
Nucleic acids research, 33(15), 4865-4873 (2005-09-06)
The mechanism by which HIV-1 reverse transcriptase (HIV-RT) discriminates between the correct and incorrect nucleotide is not clearly understood. Chemically modified nucleotides containing 1-aminonaphthalene-5-sulfonate (ANS) attached to their gamma-phosphate were synthesized and used to probe nucleotide selection by this error
Y T Kim et al.
The Journal of biological chemistry, 263(27), 13712-13717 (1988-09-25)
Physical interactions between pyridoxal kinase and aspartate aminotransferase were detected by means of emission anisotropy and affinity chromatography techniques. Binding of aspartate aminotransferase (apoenzymes) to pyridoxal kinase tagged with a fluorescent probe was detected by emission anisotropy measurements at pH
J Fick et al.
European journal of biochemistry, 126(2), 367-372 (1982-08-01)
Fluorescence studies of the intramolecular and intermolecular interactions between aminonaphthylsulfonate and nucleotides of uracil or adenine are described. The fluorescence originates solely from the naphthyl moiety and is intramolecularly quenched by the base, uracil being more effective than adenine. The
U Bhattacharyya et al.
The Journal of biological chemistry, 274(21), 14573-14578 (1999-05-18)
In the previous paper we demonstrated that uridine-5'-beta-1-(5-sulfonic acid) naphthylamidate (UDPAmNS) is a stacked and quenched fluorophore that shows severalfold enhancement of fluorescence in a stretched conformation. UDPAmNS was found to be a powerful competitive inhibitor (Ki = 0.2 mM)

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