Journal of reproduction and fertility, 63(2), 539-542 (1981-11-01)
An alternate co-polymer of styrene and maleic anhydride was dissolved in dimethylsulphoxide and injected into the vas deferens of rats. The polymer was retained in the vas deferens and the morphological changes detected were confined to the mucosa. When the
Journal of biomaterials science. Polymer edition, 4(6), 643-652 (1993-01-01)
The activation of human plasma prekallikrein (PKK) to kallikrein (KK), induced by the contact of blood with foreign materials, is a useful in vitro hemocompatibility test. Kallikrein is easily detected by its reaction with the chromogenic substrate H-D-Pro-Phe-Arg-pNA, which releases
A newly developed male contraceptive, styrene maleic anhydride (SMA), was injected in the vas deferens of male rhesus monkeys for safety evaluation at the dose of 100 mg (contraceptive dose, CD), 250 mg (CD x 2.5) and 500 mg (CD
International journal of andrology, 23(1), 36-42 (2000-01-13)
The feasibility of a spacing method for contraception, using Styrene Maleic Anhydride (SMA) as a vas occlusive agent, has been assessed in male langur monkeys. The vas deferens of 6 animals were occluded with 60 mg SMA in 120 microL
A new male method of contraception by injecting a polymer, styrene-maleic anhydride (SMA), into the lumen of the vas deferens has been studied on rhesus monkeys. The polymer has the dual feature that it can occlude the vas deferens lumen
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