385980

Benzoic anhydride

≥95%

• Synonym(s): Benzoyl anhydride, Benzoyl benzoate, Bis(phenylcarbonyl)ether
• Linear Formula: (C₆H₅CO)₂O
• CAS Number: 93-97-0
• Molecular Weight: 226.23
• Beilstein: 516726
• EC Number: 202-291-1
• MDL number: MFCD00003073
• UNSPSC Code: 12352100
• PubChem Substance ID: 24864062
• NACRES: NA.22

Properties

• Quality Level: 200
• Assay: ≥95%
• form: solid
• mp: 38-42 °C (lit.)
• density: 1.199 g/mL at 25 °C (lit.)
• functional group: anhydride; ester; phenyl
• SMILES string: O=C(OC(=O)c1ccccc1)c2ccccc2
• InChI: 1S/C14H10O3/c15-13(11-7-3-1-4-8-11)17-14(16)12-9-5-2-6-10-12/h1-10H
• InChI key: CHIHQLCVLOXUJW-UHFFFAOYSA-N

Description

Application

Benzoic anhydride can be used as a:

• Condensation reagent in the synthesis of carboxylic esters from carboxylic acids and alcohols.[1]
• Coupling reagent in the synthesis of macrolactones.[2]
• Acylating reagent for acylating sulfonamides, amines, alcohols, and phenols using ZSM-5-SO₃H as a catalyst.[3]

It can be also used as a reagent for the preparation of benzyl benzoate [4], benzylidene dibenzoate [5], 4-benzoyltoluene [6].

Safety Information

• Pictograms: GHS08,GHS05
• Signal Word: Danger
• Hazard Statements: H315,H318,H372
• Precautionary Statements: P260 - P264 - P280 - P302 + P352 - P305 + P351 + P338 - P314
• Hazard Classifications: Eye Dam. 1 - Skin Irrit. 2 - STOT RE 1 Inhalation
• Target Organs: Lungs
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point(F): 235.4 °F - closed cup
• Flash Point(C): 113 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves