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302023

Sigma-Aldrich

(−)-2-Oxo-4-thiazolidinecarboxylic acid

97%

Synonym(s):

(R)-(−)-2-Oxothiazolidine-4-carboxylic acid, L-(−)-2-Oxothiazolidine-4-carboxylic acid

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About This Item

Empirical Formula (Hill Notation):
C4H5NO3S
CAS Number:
Molecular Weight:
147.15
Beilstein:
4179169
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
Pricing and availability is not currently available.

Assay

97%

optical activity

[α]19/D −60°, c = 1 in H2O

mp

174 °C (dec.) (lit.)

SMILES string

OC(=O)[C@@H]1CSC(=O)N1

Application

An intermediate in the total synthesis of (+)-latrunculin A.[1]

replaced by

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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The Journal of Organic Chemistry, 57, 5292-5292 (1992)
Xian Fan et al.
Alcoholism, clinical and experimental research, 35(10), 1866-1875 (2011-05-17)
Alcohol abuse and HIV-1 infection frequently coexist, and these individuals are at high risk for serious lung infections and respiratory failure. Although alcohol ingestion and HIV-1 transgene expression have been shown to independently cause oxidative stress and disrupt alveolar epithelial
M J Clemente-Moreno et al.
Plant biology (Stuttgart, Germany), 12(1), 88-97 (2010-07-27)
The effect of treatment with benzothiadiazole (BTH) or l-2-oxothiazolidine-4-carboxylic acid (OTC), and their interaction with Plum pox virus (PPV) infection, on antioxidative metabolism of pea plants was studied at the subcellular level. PPV infection produced a 20% reduction in plant
Marta Caramés et al.
Anticancer research, 30(4), 1223-1231 (2010-06-10)
Glutathione has been implicated in growth factor-mediated chemoresistance of colon cancer cells. We evaluated the influence of hepatocyte growth factor, vascular endothelial growth factor and epidermal growth factor on the effect of 5-fluorouracil, oxaliplatin and SN-38 (the active metabolite of
Mehdi Saberi et al.
Iranian biomedical journal, 13(4), 215-221 (2009-12-01)
Using human skin-fibroblast cell line HF2FF, the efficacy of some drugs was evaluated against sulfur mustard (SM) cytotoxicity. The drugs were the sulfhydryl containing molecule including N-acetylcysteine (NAC), 2-oxo-thiazolidine-4-carboxylate (OTC) and acetaminophen as glutathione (GSH) stimulator pathway. The protective effects

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