Cardiotoxicity is a limiting factor of doxorubicin (DOX)-based anticancer therapy. Due to its beneficial effects, we investigated whether standardized extract of Melissa officinalis (MO) can attenuate doxorubicin-induced cardiotoxicity and can potentiate the efficacy of DOX against human breast cancer cells.
A commercial poly(vinylidene fluoride) flat sheet membrane was modified by surface coating with a dilute poly(vinyl alcohol) (PVA) aqueous solution followed by solid-vapor interfacial crosslinking. The resulting PVA layer increased membrane smoothness and hydrophilicity and resulted in comparable pure water
The optimization of synthetic pathways is a central challenge in metabolic engineering. OptSSeq (Optimization by Selection and Sequencing) is one approach to this challenge. OptSSeq couples selection of optimal enzyme expression levels linked to cell growth rate with high-throughput sequencing
Faceted crystals with exposed highly reactive planes have attracted intensive investigations for applications such as hydrogen production, enhanced catalytic activity, and electrochemical energy storage and conversion. Herein, we report the synthesis of mesoporous NiO crystals with dominantly exposed {110} reactive
To solve the pore-wetting problems of membrane distillation, we developed a series of three-layer composite pervaporation (PV) membranes that could be applied in direct contact mode. Specifically, a porous poly(vinylidene fluoride) (PVDF) layer was placed on top of a polytetrafluoroethylene
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