220019

3-Indoleglyoxylic acid

98%

• Synonym(s): NSC 71954
• Empirical Formula (Hill Notation): C₁₀H₇NO₃
• CAS Number: 1477-49-2
• Molecular Weight: 189.17
• EC Number: 216-029-9
• MDL number: MFCD00005625
• UNSPSC Code: 12352100
• PubChem Substance ID: 24853160
• NACRES: NA.22

Properties

• Assay: 98%
• form: solid
• mp: 217 °C (dec.) (lit.)
• functional group: carboxylic acid; ketone
• storage temp.: 2-8°C
• SMILES string: OC(=O)C(=O)c1c[nH]c2ccccc12
• InChI: 1S/C10H7NO3/c12-9(10(13)14)7-5-11-8-4-2-1-3-6(7)8/h1-5,11H,(H,13,14)
• InChI key: DWLVFWDCSFTDOD-UHFFFAOYSA-N

Description

General description

Chemiluminescence (CL) intensity of 3-indoleglyoxylic acid has been measured.

Application

3-Indoleglyoxylic acid was used in the synthesis of oxazinin-1, -2 and -3.

• Reactant for synthesis of fenbufen and ethacrynic acid derivatives
• Reactant for preparation of glyoxyl analogs of indole phytoalexins as anticancer agents
• Reactant for synthesis of tertiary amides
• Reactant for preparation of fuconojirimycin derivatives as inhibitors of α-Fucosidases
• Reactant for total synthesis of oxazinin-3 from 3-indoleglyoxylic acid via an intramolecular addition/cyclization reactions

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable