SNCA
synuclein, alpha (non A4 component of amyloid precursor)
Synonyms:
NACP, PARK1, PARK4, PD1
Species:
Human SNCA (6622), Mouse Snca (20617), Rat Snca (29219), cow SNCA (282857), naked mole-rat Snca (101700039), domestic cat SNCA (101091694), chicken SNCA (395393), sheep SNCA (100294604), dog SNCA (478478), Horse SNCA (100053270)
UniProtKB ID:
Gene ID:
- Human(6622) Summary: Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. [provided by RefSeq, Mar 2009]
- Mouse(20617) synuclein, alpha
- Rat(29219) synuclein, alpha (non A4 component of amyloid precursor)
- cow(282857) synuclein, alpha (non A4 component of amyloid precursor)
- naked mole-rat(101700039) synuclein, alpha (non A4 component of amyloid precursor)
- domestic cat(101091694) synuclein, alpha (non A4 component of amyloid precursor)
- chicken(395393) synuclein, alpha (non A4 component of amyloid precursor)
- sheep(100294604) synuclein, alpha (non A4 component of amyloid precursor)
- dog(478478) synuclein, alpha (non A4 component of amyloid precursor)
- Horse(100053270) synuclein, alpha (non A4 component of amyloid precursor)
- domestic guinea pig(100725375) synuclein, alpha (non A4 component of amyloid precursor)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-α-Synuclein Antibody, clone Syn211 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Phospho-α-Synuclein-S129 antibody produced in rabbit, ,
Species Reactivity
human
Application
western blot
Anti-Phospho-α-Synuclein-Y133 antibody produced in rabbit, ,
Species Reactivity
human, mouse
Application
western blot
Anti-phospho-alpha-synuclein (Ser129) Antibody, clone LS4-1B1, clone LS4-1B1, from mouse,
Species Reactivity
human, mouse
Application
immunohistochemistry
western blot
western blot
Anti-Synuclein α Antibody, Chemicon®, from rabbit,
Species Reactivity
human, rat
Application
immunohistochemistry
western blot
western blot
Proteins
Product Number
Description
Species
α-Synuclein E46K human, recombinant, expressed in E. coli, N-terminal histidine tagged, ≥90% (SDS-PAGE), lyophilized powder,
Species
human
α-Synuclein A53T human, recombinant, expressed in E. coli, N-terminal histidine tagged, ≥90% (SDS-PAGE), lyophilized powder,
Species
human
α-Synuclein human, recombinant, expressed in E. coli, N-terminal histidine tagged, ≥90% (SDS-PAGE), lyophilized powder,
Species
human