CRM67344

Indoxacarb

certified reference material, TraceCERT^®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

• Synonym(s): Methyl 7-chloro-2,5-dihydro-2-[N-(methoxycarbonyl)-4-(trifluoromethoxy)anilinocarbonyl]indeno[1,2-e][1,3,4]oxadiazine-4a(3H)carboxylate
• Empirical Formula (Hill Notation): C₂₂H₁₇ClF₃N₃O₇
• CAS Number: 144171-61-9
• Molecular Weight: 527.83
• MDL number: MFCD03792834
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: certified reference material; TraceCERT^®
• Quality Level: 300
• product line: TraceCERT^®
• shelf life: limited shelf life, expiry date on the label
• manufacturer/tradename: Manufactured by: Sigma-Aldrich Production GmbH, Switzerland
• format: neat
• SMILES string: COC(=O)N(C(=O)N1CO[C@]2(Cc3cc(Cl)ccc3C2=N1)C(=O)OC)c4ccc(OC(F)(F)F)cc4
• InChI: 1S/C22H17ClF3N3O7/c1-33-18(30)21-10-12-9-13(23)3-8-16(12)17(21)27-28(11-35-21)19(31)29(20(32)34-2)14-4-6-15(7-5-14)36-22(24,25)26/h3-9H,10-11H2,1-2H3/t21-/m0/s1
• InChI key: VBCVPMMZEGZULK-NRFANRHFSA-N

Description

General description

This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ.
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com
Indoxacarb is a non-systemic and chiral oxadiazine insecticide. It is a sodium channel antagonist and blocks the voltage-dependent sodium channels in the neurons thereby impairing nervous function and feeding, causing paralysis and death of the insect. Absorbed by ingestion and contact, it is used against sucking insects, mainly lepidopterans pests on a wide variety of crops.
As per Regulation (EC) No. 1107/2009, repealing directive 91/414/EEC, indoxacarb is approved for use as a plant protection agent in the European Union. The Commission Regulation (EU) 2015/845 of 27th May 2015 sets a maximum residue limit (MRL) of 0.02 mg/kg in fresh/frozen fruits and tree nuts for indoxacarb (measured as a sum of indoxacarb and its R enantiomer). Indoxacarb has to be monitored in the Multiannual Control Programme for Pesticides Residues (MACP), run within the EU and EFTA in/on products of plant origin.

Application

The certified reference material (CRM) is intended to be used as a calibrant for chromatography and other analytical techniques.
The indoxacarb CRM may also find the following uses:

• Investigate the persistence, distribution, and risk assessment of indoxacarb residues in tomato and soil samples by using gas chromatography with electron ionization mass spectrometry
• Simultaneous enantioselective analysis of cis-epoxiconazole and indoxacarb residues in different tea, black tea infusion, and soil samples by chiral HPLC coupled with tandem quadrupole time-of-flight mass spectrometry (Q-TOF/MS)
• To develop and validate a method for the determination of pesticide residues of iprovalicarb, indoxacarb, and boscalid in grape and wine samples by gas chromatography/ion trap mass spectrometry (GC/ITMS)
• Assess chili fruit samples collected at different time intervals for the presence of indoxacarb and thiamethoxam by gas-liquid chromatography-electron capture detection (GLC-ECD) and gas chromatography-mass spectrometry (GC-MS/MS)

Legal Information

TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS06,GHS08,GHS09
• Signal Word: Danger
• Hazard Statements: H301,H317,H332,H372,H410
• Precautionary Statements: P273 - P280 - P301 + P310 - P302 + P352 - P304 + P340 + P312 - P314
• Hazard Classifications: Acute Tox. 3 Oral - Acute Tox. 4 Inhalation - Aquatic Acute 1 - Aquatic Chronic 1 - Skin Sens. 1B - STOT RE 1
• Target Organs: Blood,Nervous system,Heart, Heart,Nervous system,Blood system
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable