PZ0268

AG-17724

≥98% (HPLC)

• Synonym(s): (R)-6-Fluoro--[(2-naphthalenylcarbonyl)amino]-1H-benzimidazole-2-propanoic acid, AG 17724
• Empirical Formula (Hill Notation): C₂₁H₁₆FN₃O₃
• CAS Number: 884033-66-3
• Molecular Weight: 377.37
• UNSPSC Code: 12352200
• PubChem Substance ID: 329823802
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: powder
• color: white to light brown
• solubility: DMSO: 20 mg/mL, clear (warmed)
• storage temp.: room temp
• SMILES string: OC([C@H](NC(C1=CC(C=CC=C2)=C2C=C1)=O)CC3=NC4=C(C=CC(F)=C4)N3)=O
• InChI: 1S/C21H16FN3O3/c22-15-7-8-16-17(10-15)24-19(23-16)11-18(21(27)28)25-20(26)14-6-5-12-3-1-2-4-13(12)9-14/h1-10,18H,11H2,(H,23,24)(H,25,26)(H,27,28)/t18-/m1/s1
• InChI key: NKMPZFCFXCJBEY-GOSISDBHSA-N

Description

Biochem/physiol Actions

AG-17724 is a potent peptidyl-prolyl isomerase (PPIase) Pin1 inhibitor.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable