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H7375

Sigma-Aldrich

Histamine bisphosphate monohydrate

Synonym(s):

2-(4-Imidazolyl)ethylamine diphosphate salt, 2-(4-Imidazolyl)ethylamine diphosphate salt monohydrate, Histamine diphosphate salt monohydrate

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About This Item

Empirical Formula (Hill Notation):
C5H9N3 · 2H3PO4 · H2O
CAS Number:
Molecular Weight:
325.15
Beilstein:
3744619
EC Number:
MDL number:
UNSPSC Code:
12352116
PubChem Substance ID:
NACRES:
NA.77

Quality Level

storage temp.

−20°C

SMILES string

[H]O[H].OP(O)(O)=O.OP(O)(O)=O.NCCc1c[nH]cn1

InChI

1S/C5H9N3.2H3O4P.H2O/c6-2-1-5-3-7-4-8-5;2*1-5(2,3)4;/h3-4H,1-2,6H2,(H,7,8);2*(H3,1,2,3,4);1H2

InChI key

CNSGLKZGHLZDHQ-UHFFFAOYSA-N

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Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Min Zhou et al.
Molecular pain, 20, 17448069241258113-17448069241258113 (2024-05-15)
Background: Recent studies have demonstrated that activated microglia were involved in the pathogenesis of central sensitization characterized by cutaneous allodynia in migraine. Activation of microglia is accompanied by increased expression of its receptors and release of inflammatory mediators. Acupuncture and
Nigar Keles et al.
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 64(7-8), 713-716 (2011-02-15)
Histamine is an endogenous biogenic amine that is synthesized from the basic amino acid histidine. Ability to mimic anaphylaxis is one of the first described functions of histamine and it has been demonstrated that histamine plays a significant role in
P Marshik et al.
Chest, 115(1), 194-199 (1999-01-30)
To determine optimal storage conditions for histamine diphosphate (HDP) solutions used for bronchoprovocation. HDP was dissolved in buffered saline solution to concentrations of 0.125 to 16 mg/mL and stored in 3-mL unit dose syringes at different temperatures for varying lengths
Y Larivée et al.
The Journal of otolaryngology, 30(6), 319-323 (2002-01-05)
The objectives of this study were to evaluate the reproducibility of the nasal response to histamine with the acoustic rhinometer and to compare the responses in normal and rhinitic subjects. Our study comprised 10 normal and 10 rhinitic subjects. Each
L Shall et al.
Acta dermato-venereologica, 71(3), 199-204 (1991-01-01)
Terfenadine is a safe non-sedative H1-receptor antagonist. This study aimed to quantify the relative reduction in weal and flare area, thickness and erythema at 4, 8, 12 and 24 h following a single but variable oral dose of terfenadine compared

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