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D4266

Sigma-Aldrich

3-(Decyldimethylammonio)­propane­sulfonate inner salt

zwitterionic detergent

Synonym(s):

Caprylyl sulfobetaine, SB3-10

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About This Item

Linear Formula:
CH3(CH2)9N+(CH3)2CH2CH2CH2SO3-
CAS Number:
15163-36-7
Molecular Weight:
307.49
Beilstein:
3967284
MDL number:
MFCD00036908
UNSPSC Code:
12161900
PubChem Substance ID:
24893849
NACRES:
NA.25

Quality Level

200

Assay

≥98.0% (TLC)

form

powder

mol wt

micellar avg mol wt 12,600

aggregation number

41

technique(s)

enzyme immunoassay: suitable
protein purification: suitable
protein quantification: suitable

conductivity

<20 μmho per cm at 24 °C (0.1 M aqueous solution)

CMC

25-40 mM (20-25°C)

SMILES string

CCCCCCCCCC[N+](C)(C)CCCS([O-])(=O)=O

InChI

1S/C15H33NO3S/c1-4-5-6-7-8-9-10-11-13-16(2,3)14-12-15-20(17,18)19/h4-15H2,1-3H3

InChI key

WKALLSVICJPZTM-UHFFFAOYSA-N

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General description

3-(Decyldimethylammonio)­propane­sulfonate inner salt, a zwitterionic surfactant, is a sulfobetaine. Sulfobetaines contain a positively charged quaternary ammonium group and a negatively charged sulfonic group.

Application

3-(Decyldimethylammonio)­propane­sulfonate inner salt was used:
  • In a study to demonstrate a polyurethane chip that electrostatically binds to immunoglobulin G (IgG).
  • In a study to describe a method for isolating a high yield of Arabidopsis chloroplasts.
  • Solubilization of oleosins.
Zwitterionic detergent used for protein solubilization.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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W Schulz et al.
Journal of steroid biochemistry, 32(4), 581-590 (1989-04-01)
11 beta-hydroxysteroid dehydrogenase (11-HSD, EC 1.1.1.146) from rat renal cortex microsomes was solubilized using several detergents, the most effective being Zwittergent 3-10 and Triton X-100. The activity ratio oxidation/reduction of the reversible reaction corticosterone in equilibrium 11-dehydrocoticosterone varied depending on
Sybille E Kubis et al.
Methods in molecular biology (Clifton, N.J.), 425, 171-186 (2008-03-29)
A major area of research in the postgenomic era has been the proteomic analysis of various subcellular and suborganellar compartments. The success of these studies is to a large extent dependent upon efficient protocols for the preparation of highly pure
Kenji Murakami et al.
The Journal of biological chemistry, 288(9), 6325-6332 (2013-01-11)
Whereas individual RNA polymerase II (pol II)-general transcription factor (GTF) complexes are unstable, an assembly of pol II with six GTFs and promoter DNA could be isolated in abundant homogeneous form. The resulting complete pol II transcription preinitiation complex (PIC)
Effects of long-chains of zwitterionic micelles on binding constants of triflusal and acetylsalicylic acid.
Ferrit M, et al.
Colloids and Surfaces. A, Physicochemical and Engineering Aspects, 345(1), 26-30 (2009)
Solubilization conditions for hydrophobic membrane protein, oleosin, in soybeans
Kim, H., et al.
Biotechnology and Bioprocess Engineering: BBE, 12, 542-542 (2007)
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