P35200
Phenylsuccinic acid
98%
Synonym(s):
(±)-Phenylsuccinic acid
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About This Item
Linear Formula:
HO2CCH2CH(C6H5)CO2H
CAS Number:
Molecular Weight:
194.18
Beilstein:
1875051
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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Quality Level
Assay
98%
form
powder
mp
166-168 °C (lit.)
SMILES string
OC(=O)CC(C(O)=O)c1ccccc1
InChI
1S/C10H10O4/c11-9(12)6-8(10(13)14)7-4-2-1-3-5-7/h1-5,8H,6H2,(H,11,12)(H,13,14)
InChI key
LVFFZQQWIZURIO-UHFFFAOYSA-N
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Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Younghye Kim et al.
Advanced science (Weinheim, Baden-Wurttemberg, Germany), 7(3), 1900137-1900137 (2020-02-12)
The carboxylation of hydrocarbons using CO2 as a one-carbon building block is an attractive route for the synthesis of carboxylic acids and their derivatives. Until now, chemical carboxylation catalyzed by organometallic nucleophiles and reductants has been generally adopted particularly for
T Bruhn et al.
Journal of neuroscience research, 46(2), 198-203 (1996-10-15)
Swelling-induced release of taurine was investigated in vivo in hippocampus by microdialysis or in vitro in cultured neocortical neurons or astrocytes. Swelling was induced either by increasing the extracellular K+ concentration or by exposing the cells to hyposmotic conditions. It
R Huang et al.
Neuroscience letters, 183(1-2), 22-26 (1995-01-02)
Phenylsuccinate is an inhibitor of cytosolic glutamate formation from extracellular glutamine in cultured cerebellar granule cell neurons, a glutamatergic preparation. It prevents anoxic cell death in these cells as indicated by decreased lactate dehydrogenase (LDH) release and by the morphological
G K Asimakis et al.
The American journal of physiology, 249(5 Pt 2), H1009-H1016 (1985-11-01)
Adenine nucleotide efflux from isolated rat heart mitochondria was studied. Inorganic phosphate induced efflux of adenine nucleotides from the mitochondria. This efflux was inhibited by carboxyatractyloside and atractyloside. The rate of efflux showed saturation kinetics with respect to extramitochondrial phosphate
Heather M Wilkins et al.
The Journal of biological chemistry, 288(7), 5091-5101 (2013-01-04)
Mitochondrial oxidative stress significantly contributes to the underlying pathology of several devastating neurodegenerative disorders. Mitochondria are highly sensitive to the damaging effects of reactive oxygen and nitrogen species; therefore, these organelles are equipped with a number of free radical scavenging
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