Skip to Content
Merck
All Photos(1)

Documents

531472

Sigma-Aldrich

2-Iodophenylacetic acid

97%

Sign Into View Organizational & Contract Pricing


About This Item

Linear Formula:
IC6H4CH2CO2H
CAS Number:
Molecular Weight:
262.04
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

97%

mp

116-119 °C (lit.)

SMILES string

OC(=O)Cc1ccccc1I

InChI

1S/C8H7IO2/c9-7-4-2-1-3-6(7)5-8(10)11/h1-4H,5H2,(H,10,11)

InChI key

IUHXGZHKSYYDIL-UHFFFAOYSA-N

General description

2-Iodophenylacetic acid is a substituted acetic acid that can be prepared from 2-iodobenzyl cyanide. It undergoes palladium-catalyzed reaction with allenes to form 1,3-butadienes. 2-Iodophenylacetic acid also undergoes photolysis in carbon tetrachloride to form the corresponding chloro compound.

Application

2-Iodophenylacetic acid may be used in the preparation of:
  • 2-iodophenylacetyl chloride
  • 3,4-dimethoxyphenyl 2-iodophenylacetate
  • N-{2-[2-(2-iodophenyl)-acetylamino]-ethyl}-2-(3,4- dichlorophenyl)-acetamide

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Regioselective Synthesis of Isoquino [1,2-b][3] benzazepines (Homoprotoberberines) through 11-Membered-Ring Stilbene Lactams Obtained by Radical Macrocyclization.
Rodriguez G, et al.
The Journal of Organic Chemistry, 64(13), 4830-4833 (1999)
Photochemical synthesis of aromatic chloro compounds from aromatic iodo compounds.
The Journal of Organic Chemistry, 35(2), 528-529 (1970)
Synthesis of benzo[c]chromen-6-ones via novel cyclic aryl?Pd (II)?ester enolate intermediates.
Taylor SR, et al.
Tetrahedron, 63(45), 10889-10895 (2007)
Pd?Catalyzed Reactions of Allenylphosphonates and Related Allenes with Functionalized 2?Iodophenols, 2?Iodobenzoic Acid, and 2?Iodobenzyl Alcohol Leading to Functionalized Benzofurans, Isocoumarins, and Benzopyrans.
Pavan MP, et al.
European Journal of Organic Chemistry, 5927-5940 (2009)
Jonathan M Fitzsimmons et al.
Medicinal chemistry, 1(102) (2011-12-25)
Eight halogenated

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service