11715
Sodium barbiturate
≥97.0% (T)
Synonym(s):
Barbituric acid sodium salt
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About This Item
Empirical Formula (Hill Notation):
C4H3N2NaO3
CAS Number:
Molecular Weight:
150.07
Beilstein:
3748030
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
Recommended Products
Assay
≥97.0% (T)
solubility
hot water: soluble 0.2 g/10 mL, clear, colorless
SMILES string
[Na+].[O-]C1=NC(=O)NC(=O)C1
InChI
1S/C4H4N2O3.Na/c7-2-1-3(8)6-4(9)5-2;/h1H2,(H2,5,6,7,8,9);/q;+1/p-1
InChI key
MHQHHBYRYFICDV-UHFFFAOYSA-M
Related Categories
General description
Sodium barbiturate is a white to light beige powder. It accelerates the propagation of metastatic prostate adenocarcinomas in rats and in tissue culture.
Application
Sodium barbiturate has been used for quantification of thrombin in plasma. It has been used in the estimation of trypsin in duodenal contents. It was also used as a buffer to characterise the functions of two long-chain fatty acid CoA ligase genes (facl) in crude oil-degrading Geobacillus thermodenitrificans NG80-2.
Other Notes
Sales restrictions may apply
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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M Pollard et al.
Oncology, 34(3), 129-132 (1977-01-01)
Metastatic prostate adenocarcinomas, derived from aging germfree Wistar rats, have been propagated in rats and in tissue culture. A protocol has been developed and demonstrated for assay of treatments which retard or which accelerate the rate and extent of tumor
F A Ofosu et al.
Blood, 64(3), 742-747 (1984-09-01)
Heparan with a low affinity for antithrombin III has previously been demonstrated to inhibit thrombin generation in both normal plasma and plasma depleted of antithrombin III. In addition, standard heparin and heparin with a low affinity for antithrombin III have
Simple method for estimating trypsin.
H S Wiggins
Gut, 8(4), 415-416 (1967-08-01)
Vadivel Parthsarathy et al.
PloS one, 8(1), e54769-e54769 (2013-02-06)
Previously, we have developed a retro-inverso peptide inhibitor (RI-OR2, rGffvlkGr) that blocks the in vitro formation and toxicity of the Aβ oligomers which are thought to be a cause of neurodegeneration and memory loss in Alzheimer's disease. We have now
Meike Roth et al.
Journal of magnetic resonance (San Diego, Calif. : 1997), 204(1), 50-55 (2010-03-09)
Significant (13)C NMR signal enhancement by a factor of 5000 of a barbituric acid derivative (5-methyl-5-propenyl-barbituric acid) via parahydrogen induced polarization is presented. This hyperpolarization is achieved by hydrogenating 5-methyl-5-propargyl-barbituric acid with 98% enriched para-H(2) under elevated temperature and pressure
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