Skip to Content
Merck
All Photos(2)

Key Documents

View All Documentation

SRP5239

Sigma-Aldrich

TAOK3 (1-463), active, GST tagged human

PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

Synonym(s):

DKFZp666H245, DPK, FLJ31808, JIK, MAP3K18

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

CAS Number:
253873-53-9
UNSPSC Code:
12352200
NACRES:
NA.32

biological source

human

recombinant

expressed in baculovirus infected Sf9 cells

product line

PRECISIO® Kinase

Assay

≥70% (SDS-PAGE)

form

buffered aqueous glycerol solution

specific activity

221-299 nmol/min·mg

mol wt

~89 kDa

technique(s)

inhibition assay: suitable

NCBI accession no.

NM_016281

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... TAOK3(51347)

General description

TAOK3 or TAO kinase 3 is a member of the serine/threonine-protein kinase family that inhibits the basal activity of Jun kinase and is negatively regulated by epidermal growth factor (EGF). Overexpression of TAOK3 may activate the ERK1/ERK2 and JNK/SAPK targets. TAOK3 is highly expressed in peripheral blood leukocytes (PBLs), thymus, spleen, kidney, skeletal muscle, heart and liver.

Physical form

Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

Preparation Note

after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles

Legal Information

PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
N041-1

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Jason T Yustein et al.
Oncogene, 22(40), 6129-6141 (2003-09-19)
The Sterile-20 or Ste20 family of serine/threonine kinases is a group of signaling molecules whose physiological roles within mammalian cells are just starting to be elucidated. Here, in this report we present the characterization of three human Ste20-like kinases with
E Tassi et al.
The Journal of biological chemistry, 274(47), 33287-33295 (1999-11-24)
Mammalian members related to Saccharomyces cerevisiae serine/threonine kinase STE20 can be divided into two subfamilies based on their structure and function. The PAK subfamily is characterized by an N-terminal p21-binding domain (also known as CRIB domain), a C-terminal kinase domain

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service