Skip to Content
Merck
All Photos(1)

Key Documents

D6035

Sigma-Aldrich

Disopyramide phosphate salt

Synonym(s):

α-Diisopropylaminoethyl-α-phenylpyridine-2-acetamide

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
C21H29N3O · H3PO4
CAS Number:
22059-60-5
Molecular Weight:
437.47
EC Number:
244-756-1
MDL number:
MFCD00069254
UNSPSC Code:
12352200
PubChem Substance ID:
24277706
NACRES:
NA.77

form

solid

SMILES string

OP(O)(O)=O.CC(C)N(CCC(C(N)=O)(c1ccccc1)c2ccccn2)C(C)C

InChI

1S/C21H29N3O.H3O4P/c1-16(2)24(17(3)4)15-13-21(20(22)25,18-10-6-5-7-11-18)19-12-8-9-14-23-19;1-5(2,3)4/h5-12,14,16-17H,13,15H2,1-4H3,(H2,22,25);(H3,1,2,3,4)

InChI key

CGDDQFMPGMYYQP-UHFFFAOYSA-N

Gene Information

human ... SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335)

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

Disopyramide phosphate salt has been used as an internal standard for plasma sample analysis by mass spectrometry. It might be used as a test compound in a teratogenicity study.

Biochem/physiol Actions

Class IA antiarrhythmic; sodium channel blocker
Disopyramide is found to stabilize the cell membrane by altering the action potential. It might act as an antiarrhythmic agent.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Precautionary Statements

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
018F0560

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

0
Drugs for Pregnant and Lactating Women, 252-338 (2009)
Akihito Yamashita et al.
The Journal of toxicological sciences, 39(3), 453-464 (2014-05-23)
The zebrafish has been considered as a suitable animal model for drug discovery, especially for evaluation of the teratogenicity, due to their small size, rapid development, transparency, and developmental similarities to mammalian development. These features of zebrafish make it possible
Anthony A Fossa et al.
The Journal of pharmacology and experimental therapeutics, 302(2), 828-833 (2002-07-20)
QT interval prolongation of the electrocardiogram has been associated with the occurrence of life-threatening fatal ventricular arrhythmias. To understand the relationship between preclinical cardiac conduction assessment to clinical outcome, comparisons of free (unbound)-plasma drug concentrations and their associated effects in
Isuru Ranasinghe et al.
Heart, lung & circulation, 20(9), 579-586 (2011-06-21)
Negative ionotropic agents are established treatments for left ventricular outflow tract obstruction (LVOTO) in hypertrophic cardiomyopathy (HCM). However, their benefit in those with LVOTO without typical HCM is unclear. We evaluated if negative ionotropic agents are beneficial in treatment of
Takashi Komatsu et al.
Circulation journal : official journal of the Japanese Circulation Society, 74(9), 1859-1865 (2010-07-16)
It has been reported that approximately one-third of patients undergoing cardiovascular surgery experience paroxysmal atrial fibrillation (AF) during the postoperative period. There is, however, little information on the selection of anti-arrhythmic drugs for terminating postoperative paroxysmal AF. Between April 2007
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service