Skip to Content
Merck
All Photos(1)

Key Documents

239305

Sigma-Aldrich

Sodium hypochlorite solution

reagent grade, available chlorine 4.00-4.99 %

Sign Into View Organizational & Contract Pricing


About This Item

Linear Formula:
NaClO
CAS Number:
Molecular Weight:
74.44
EC Number:
MDL number:
UNSPSC Code:
12352300
PubChem Substance ID:
NACRES:
NA.21

grade

reagent grade

Agency

suitable for SM 4500 - NH3

vapor pressure

17.5 mmHg ( 20 °C)

form

liquid

composition

available chlorine, 4.00-4.99%

reaction suitability

reagent type: oxidant

concentration

4.00-4.99% (chlorine by Na2S2O3, titration)

density

1.097 g/mL at 25 °C

storage temp.

2-8°C

SMILES string

[Na+].[O-]Cl

InChI

1S/ClO.Na/c1-2;/q-1;+1

InChI key

SUKJFIGYRHOWBL-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

Sodium hypochlorite (NaOCl) is a commonly used reagent in organic synthesis for many oxidation and chlorination reactions.

Application

Sodium hypochlorite solution can be used as an oxidizing agent for the oxidation of:      
  • Primary alcohols to aldehydes or carboxylic acids and secondary alcohols to ketones.     
  • Aryl aldehydes to the corresponding acids in the presence of a phase-transfer catalyst.      
  • Ethers to esters by careful pH control (pH range of 8–9.5),

It can also be used as a reagent in the:      
  • Epoxidation of enones and polycyclic arenes.      
  • Oxidative degradation reaction      
  • N-Chlorination of primary and secondary amines
  • Enantioselective epoxidation of α, β-unsaturated ketones      
  • Asymmetric dihydroxylation of olefins in the presence of an osmium catalyst      
  • Chlorination of allylic carbons in the presence of CeCl3

Features and Benefits

  • Readily available reagent      
  • Easily handled oxidizing agent      
  • No phase-transfer catalyst is necessary for the oxidation of substrates in the pH range 10–11     
  • Simplified waste disposal and lower toxicity

Disclaimer

“The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.”

Pictograms

CorrosionEnvironment

Signal Word

Danger

Hazard Statements

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Isolation of Epithelial Cells from Mouse Gastrointestinal Tract for Western Blot or RNA Analysis.
Zeineldin M and Neufeld K.
Bio-protocol, 2(22) (2012)
Bingying Leng et al.
Plant science : an international journal of experimental plant biology, 302, 110704-110704 (2020-12-09)
Arabidopsis thaliana TRY is a negative regulator of trichome differentiation that promotes root hair differentiation. Here, we established that LbTRY, from the recretohalophyte Limonium bicolor, is a typical MYB transcription factor that exhibits transcriptional activation activity and locates in nucleus.
Sodium Hypochlorite
Galvin JM and Jacobsen EN
eEROS (Encyclopedia of Reagents for Organic Synthesis) (2001)
Collection of Root Exudate from Duckweed.
Lu Y, et al.
Bio-protocol, 5(1) (2015)
B R Johnson et al.
Journal of endodontics, 19(1), 40-43 (1993-01-01)
Although the tissue solvent and bactericidal properties of sodium hypochlorite are well known, the effective shelf-life of prepared sodium hypochlorite solutions is not known. The stability of sodium hypochlorite is adversely affected by exposure to high temperature, light, air, and

Related Content

This page is intended to make it easier to find the consumables you need based on the analytical method you’re using. Methods included on this page come from the EPA, Standard Methods and ASTM.

This page is intended to make it easier to find the consumables you need based on the analytical method you’re using. Methods included on this page come from the EPA, Standard Methods and ASTM.

This page is intended to make it easier to find the consumables you need based on the analytical method you’re using. Methods included on this page come from the EPA, Standard Methods and ASTM.

This page is intended to make it easier to find the consumables you need based on the analytical method you’re using. Methods included on this page come from the EPA, Standard Methods and ASTM.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service