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AmberChrom 50WX4 Ion Exchange Resin

hydrogen form, 100-200 mesh

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About This Item

Linear Formula:
(C10H12 · C10H10 · C8H8)x
CAS Number:
MDL number:
UNSPSC Code:
12000000
NACRES:
SB.52
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Product Name

AmberChrom 50WX4 hydrogen form, hydrogen form, 100-200 mesh

description

cross-linkage 4%

Quality Level

form

beads

moisture

64-72%

technique(s)

LPLC: suitable

matrix

styrene-divinylbenzene (gel)

matrix active group

sulfonic acid functional group

particle size

100-200 mesh

capacity

1.1 meq/mL by wetted bed volume

separation technique

cation exchange

SMILES string

C(C)c3c(cccc3)C=C.c2(c(cccc2)C=C)C=C.c1(ccccc1)C=C

InChI

1S/C10H12.C10H10.C8H8/c2*1-3-9-7-5-6-8-10(9)4-2;1-2-8-6-4-3-5-7-8/h3,5-8H,1,4H2,2H3;3-8H,1-2H2;2-7H,1H2

InChI key

NWUYHJFMYQTDRP-UHFFFAOYSA-N

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General description

Dowex 50WX4 hydrogen form is a nonmacroporous gelform bead resin.[1] Dowex 50WX4 hydrogen form can be used as a column packing material which is used in anion exchange chromatography.[2]

Application

Dowex 50WX4 hydrogen form was used:
  • to investigate the effect of particle size on drug loading and release profiles[3]
  • for the conversion of D,L-Glyceraldehyde 3-phosphate diethyl acetal (barium salt) on treatment with boiling water to free aldehyde D,L-glyceraldehyde 3-phosphate[4]
Strongly acidic cation exchange resin that meets requirements of FDA Food Additive Regulation 21 CFR 173.25
Used for the recovery of useful radioactive species from waste nuclear material.[5]

Other Notes

This strongly acidic cation exchange resin has not been specially processed nor cleaned. We suggest that it be subjected to a suitable preliminary elution and wash.

Legal Information

Amberchrom is a trademark of DuPont de Nemours, Inc.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Mohapatra, P.K., et al.
Solvent Extr. Ion Exch., 22, 267-267 (2004)
Superacid polymers: Synthesis and analysis of AlCl3-sulfonic acid resin complexes.
Magnotta, V. L., and B. C. Gates.
Journal of Polymer Science Part A: Polymer Chemistry, 15, 1341-1347 (1977)
Maybelle K Go et al.
Biochemistry, 48(24), 5769-5778 (2009-05-12)
Product distributions for the reaction of glycolaldehyde labeled with carbon-13 at the carbonyl carbon ([1-(13)C]-GA) catalyzed by triosephosphate isomerase (TIM) in D(2)O at pD 7.0 in the presence of phosphite dianion and in its absence were determined by (1)H NMR
Sebastian Reichau et al.
The Journal of biological chemistry, 286(18), 16197-16207 (2011-04-02)
Tuberculosis remains a serious global health threat, with the emergence of multidrug-resistant strains highlighting the urgent need for novel antituberculosis drugs. The enzyme 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (DAH7PS) catalyzes the first step of the shikimate pathway for the biosynthesis of aromatic
Seong Hoon Jeong et al.
International journal of pharmaceutics, 361(1-2), 26-32 (2008-06-21)
Complexes of ion-exchange resins and dextromethorphan (DM), a model drug, were prepared using different methods including a batch and a column method with different functional groups, ion-exchange capacity, degree of crosslinking, and resin particle size. Drug loading efficiency, release profiles

Questions

1–3 of 3 Questions  
  1. How can I regenerate/activate the resin for exchanging doxorubicin

    1 answer
    1. Prior to use, the resin should be washed and the fines removed. Transfer approximately 100 g of resin to a 500 mL beaker. Add deionized water to cover the resin bed by several inches. Stir or swirl the resin gently for a minute to ensure complete mixing (do not use a stir bar). Allow the material to stand for 15-20 minutes. Decant most of the water and replace it with fresh deionized water. Stir the mixture and allow it to settle for 5-10 minutes. Decant and rinse the resin 3 times with deionized water to remove any residual fines or color. Following this, the resin needs to be regenerated into hydrogen form. Using 1N HCl or H2SO4 (deionized water), slowly add sufficient quantity to cover the resin bed by 1-2 inches and stir or swirl the resin gently for a minute to ensure complete mixing (do not use stir bar). Allow the material to stand for 5-10 minutes. Decant most of the acid and repeat the above twice more with fresh 1N acid. Decant most of the acid and rinse at least 5 times with deionized water [rinse to pH>4.8]. Please note that if methanol or some other aqueous miscible solvent is going to be used in the elution of components from the resin, the above procedure should be repeated in that solvent, to remove residual monomers and color components. The resin must be equilibrated in the sample solvent prior to use.

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  2. How can I convert a cation exchange resin from the hydrogen form to the sodium form?

    1 answer
    1. To convert a cation exhcange resin from the hydrogen form to the sodium form, use two to four bed volumes of 0.5-2.0% NaCl or NaOH.

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  3. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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