Skip to Content
Merck
All Photos(1)

Documents

890704P

Avanti

18:1 EPC (Cl Salt)

Avanti Research - A Croda Brand

Synonym(s):

1,2-dioleoyl-sn-glycero-3-ethylphosphocholine (chloride salt)

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C46H89NO8PCl
CAS Number:
Molecular Weight:
850.63
UNSPSC Code:
12352211
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 100 mg (890704P-100mg)
pkg of 2 × 100 mg (890704P-200mg)
pkg of 1 × 25 mg (890704P-25mg)

manufacturer/tradename

Avanti Research - A Croda Brand

lipid type

cationic lipids
transfection

shipped in

dry ice

storage temp.

−20°C

SMILES string

O=P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O)OCC.[Cl-]

General description

18:1 EPC (Cl Salt) is a cationic lipid.

Application

18:1 EPC (Cl Salt) is suitable:
  • for the preparation of lipid-nanoparticles
  • for the use with 90% of 1,2-dioleoyl-sn-glycero-3-ethylphosphocholine (DOPC) to produce doped giant unilamellar vesicles
  • as an emulsifier to study it′s in vitro transfection activity with respect to cationic lipid changes

Packaging

5 mL Clear Glass Sealed Ampule (890704P-100mg)
5 mL Clear Glass Sealed Ampule (890704P-200mg)
5 mL Clear Glass Sealed Ampule (890704P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Enhanced intrapulmonary delivery of anticancer siRNA for lung cancer therapy using cationic ethylphosphocholine-based nanolipoplexes
Shim G, et al.
Molecular Therapy, 21(4), 816-824 (2013)
Optimization of lipid composition in cationic emulsion as in vitro and in vivo transfection agents
Kim TW, et al.
Pharmaceutical Research, 18(1), 54-60 (2001)
Controlling loading and optical properties of gold nanoparticles on liposome membranes
Sau TK, et al.
Colloids and Surfaces. A, Physicochemical and Engineering Aspects, 342(1-3), 92-96 (2009)
Lipid nanoparticles for delivery of messenger RNA to the back of the eye
Patel S, et al.
J. Controlled Release, 303, 91-100 (2019)
Kabir H Biswas et al.
Langmuir : the ACS journal of surfaces and colloids, 34(4), 1775-1782 (2017-12-28)
The pathway of vesicle adsorption onto a solid support depends on the material composition of the underlying support, and there is significant interest in developing material-independent strategies to modulate the spectrum of vesicle-substrate interactions on a particular surface. Herein, using

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service