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860608P

Avanti

N-02:0 Phytosphingosine

Avanti Research™ - A Croda Brand 860608P, powder

Synonym(s):

N-acetoyl 4-hydroxysphinganine (Saccharomyces Cerevisiae)

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About This Item

Empirical Formula (Hill Notation):
C20H41NO4
CAS Number:
475995-69-8
Molecular Weight:
359.54
UNSPSC Code:
12352211
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 5 mg (860608P-5mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 860608P

lipid type

sphingolipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

O[C@]([H])(CCCCCCCCCCCCCC)[C@](O)([H])[C@@]([H])(NC(C)=O)CO

InChI

1S/C20H41NO4/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-19(24)20(25)18(16-22)21-17(2)23/h18-20,22,24-25H,3-16H2,1-2H3,(H,21,23)

InChI key

SZUJJDLBXJCDNT-UHFFFAOYSA-N

General description

Phytosphingosine is a sphingoid base with hydroxyl group at the C4 position. It is highly found in plants and fungi. In addition, phytosphingosine is also present in mammalian epidermis, including the stratum corneum.

Biochem/physiol Actions

Phytosphingosine acts as a sphingoid backbone for phytoceramide, which is a yeast analogue of the mammalian ceramide. Phytosphingosine and its derivatives are allied with body′s natural defense system. These lipids prevent dehydration of skin, control epidermal cell growth, differentiation, and apoptosis. In addition, they also exhibit anti-bactericidal and anti-inflammatory activities. Thus, Phytosphingosine and its derivatives is essential for maintaining healthy skin. But, at high concentrations these compounds are toxic.

Packaging

5 mL Amber Glass Screw Cap Vial (860608P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Ceramide function in the brain: when a slight tilt is enough
Mencarelli C and Martinez-Martinez, P
Cellular and Molecular Life Sciences, 70(2), 181-203 (2013)
Byung-Hak Kim et al.
The Journal of investigative dermatology, 134(4), 1023-1032 (2013-11-02)
Phytosphingosine is abundant in plants and fungi and is found in mammalian epidermis, including the stratum corneum. Phytosphingosine and its derivatives N-acetyl phytosphingosine and tetraacetyl phytosphingosine are part of the natural defense system of the body. However, these molecules exhibit

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