PHL89825
Wogonin
phyproof® Reference Substance
Synonym(s):
5,7-Dihydroxy 8-methoxyflavone
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About This Item
Empirical Formula (Hill Notation):
C16H12O5
CAS Number:
Molecular Weight:
284.26
MDL number:
UNSPSC Code:
41116107
NACRES:
NA.24
Pricing and availability is not currently available.
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grade
primary reference standard
product line
phyproof® Reference Substance
Assay
≥95.0% (HPLC)
manufacturer/tradename
PhytoLab
application(s)
food and beverages
format
neat
SMILES string
O1c2c(c(cc(c2OC)O)O)C(=O)C=C1c3ccccc3
InChI
1S/C16H12O5/c1-20-15-12(19)7-10(17)14-11(18)8-13(21-16(14)15)9-5-3-2-4-6-9/h2-8,17,19H,1H3
InChI key
XLTFNNCXVBYBSX-UHFFFAOYSA-N
Related Categories
General description
This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG
Legal Information
phyproof is a registered trademark of PhytoLab GmbH & Co. KG
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Yong Wang et al.
Frontiers in pharmacology, 11, 1152-1152 (2020-08-15)
Wogonin, an active component derived from Scutellaria baicalensis, has shown anti-tumor activities in several malignancies. However, the roles of wogonin in RCC cells remain elusive. Here, we explored the effects of wogonin on RCC cells and the underlying mechanisms. We
Wogonin glucuronidation in liver and intestinal microsomes of humans, monkeys, dogs, rats, and mice.
Nobumitsu Hanioka et al.
Xenobiotica; the fate of foreign compounds in biological systems, 50(8), 906-912 (2020-02-02)
Wogonin, one of the flavonoids isolated from Scutellaria baicalensis, exhibits some beneficial bioactivities, including anti-inflammatory and anticancer effects, and is metabolized into glucuronide by UDP-glucuronosyltransferase (UGT) enzymes in humans. In the present study, wogonin glucuronidation was examined in the liver
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Therapeutic treatment options for opportunistic non-tuberculous mycobacterial (NTM) infection and/or serious mycobacterial infections such as tuberculosis (TB) and leprosy are limited due to the spread of antimicrobial resistance mechanism. Plant-derived natural compounds as prospective efflux pump inhibitors may present a
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